Asada Shohei, Douhara Akitoshi, Murata Koji, Yanase Koji, Tsutsumi Masahiro, Yoshiji Hitoshi
Department of Internal Medicine, Saiseikai Chuwa Hospital, Japan.
Department of Pathology, Saiseikai Chuwa Hospital, Japan.
Intern Med. 2019 Mar 1;58(5):667-673. doi: 10.2169/internalmedicine.1299-18. Epub 2018 Oct 17.
Both autoimmune hepatitis (AIH) and eosinophilic fasciitis (EF) are known to be complicated by other autoimmune diseases. However, AIH complicated by EF has never been reported. We experienced a 58-year-old man with AIH complicated by EF. He was admitted to our hospital with acute hepatic injury and edema of the legs in April 201X. The etiologies of these symptoms were histologically proven as AIH and EF. The administration of prednisolone (PSL) drastically improved his liver injury and edema of the legs. When we make a diagnosis of AIH, we should carefully evaluate the physical findings, including the appearance of the legs, in order to detect other coexisting autoimmune diseases.
自身免疫性肝炎(AIH)和嗜酸性筋膜炎(EF)均已知会并发其他自身免疫性疾病。然而,AIH并发EF的情况此前从未有过报道。我们接诊了一名58岁并发EF的AIH男性患者。他于201X年4月因急性肝损伤和腿部水肿入院。这些症状的病因经组织学证实为AIH和EF。泼尼松龙(PSL)治疗使他的肝损伤和腿部水肿得到了显著改善。在诊断AIH时,我们应仔细评估体格检查结果,包括腿部外观,以便发现其他并存的自身免疫性疾病。