Emerg Infect Dis. 2018 Nov;24(11):1998-2002. doi: 10.3201/eid2411.180787.
Cryptococcus gattii traditionally infects immunocompetent hosts and causes devastating pulmonary or central nervous system disease. However, this infection rarely occurs in patients infected with HIV. We report 3 cases of HIV-associated C. gattii complex infections in the southeastern United States. Detection of C. gattii in HIV-infected patients in this region warrants increased awareness of this threat to ensure appropriate diagnosis and treatment to optimize patient outcomes.
新型隐球菌通常感染免疫功能正常的宿主,引起肺部或中枢神经系统的破坏性疾病。然而,这种感染在感染 HIV 的患者中很少发生。我们报告了美国东南部的 3 例 HIV 相关的新型隐球菌复合体感染病例。在该地区 HIV 感染患者中检测到新型隐球菌,需要提高对这一威胁的认识,以确保进行适当的诊断和治疗,优化患者的预后。