Wang Kun, Yu Feidan, Chen Keng, Niu Huanjiang, Wang Yirong, Yang Shuxu, Cai Xiujun
Department of Neurosurgery.
Department of Radiology, Hangzhou Xiasha Hospital.
Medicine (Baltimore). 2018 Oct;97(42):e12803. doi: 10.1097/MD.0000000000012803.
Osteoblastoma is an uncommon primary bone tumor that involves any part of the skeleton. But its occurrence in the skull is extremely rare.
A 30-year-old female was admitted to our hospital, because of the mass in the right frontal region with the history of headache for 3 years without nausea or vomiting.
Initial differential diagnoses included hemangiopericytoma, atypical intraosseous meningioma, calvarial osteosarcoma, fibrous dysplasia, and histiocytosis, based on the results of enhanced CT and MRI.
A total surgical resection of the mass was performed.
Postoperative histopathologic analysis demonstrated the typical features of osteoblastoma, the benign bone neoplasm. Serial radiologic examination did not show recurrence in the 6 months follow-up.
The radiologic appearance of the osteoblastoma is always confusing and makes the diagnosis difficult. We hope our case can give some clinical clues for the diagnosis and management of the disease.
骨母细胞瘤是一种罕见的原发性骨肿瘤，可累及骨骼的任何部位。但其发生于颅骨极为罕见。
一名30岁女性因右额部肿物伴3年头痛史入院，无恶心或呕吐症状。
根据增强CT和MRI结果，初步鉴别诊断包括血管外皮细胞瘤、非典型骨内脑膜瘤、颅骨骨肉瘤、骨纤维发育不良和组织细胞增多症。
对肿物进行了完整手术切除。
术后组织病理学分析显示为骨母细胞瘤的典型特征，即良性骨肿瘤。系列影像学检查在6个月随访中未显示复发。
骨母细胞瘤的影像学表现常常令人困惑，导致诊断困难。我们希望我们的病例能为该疾病的诊断和治疗提供一些临床线索。
