Suppr超能文献

远程酒精监测促进基于激励的酒精使用障碍治疗:一项随机试验。

Remote Alcohol Monitoring to Facilitate Incentive-Based Treatment for Alcohol Use Disorder: A Randomized Trial.

机构信息

Virginia Tech Carilion Research Institute, Virginia Tech, Roanoke, Virginia.

Psychiatry and Behavioral Sciences, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.

出版信息

Alcohol Clin Exp Res. 2018 Dec;42(12):2423-2431. doi: 10.1111/acer.13891. Epub 2018 Oct 18.

Abstract

BACKGROUND

The delivery of monetary incentives contingent on verified abstinence is an effective treatment for alcohol use disorder. However, technological barriers to accurate, frequent biochemical verification of alcohol abstinence have limited the dissemination of this technique.

METHODS

In the present randomized parallel trial, we employed a breathalyzer that allows remote, user-verified collection of a breath alcohol sample, text messaging, and reloadable debit cards for remote delivery of incentives to evaluate a contingency management treatment for alcohol use disorder that can be delivered with no in-person contact. Treatment-seeking participants with alcohol use disorder (n = 40) were recruited from the community and randomized to either a contingent or a noncontingent group (n = 20 each). The contingent group received nearly immediate monetary incentives each day they remotely provided negative breathalyzer samples. The noncontingent group received matched monetary payments each day they successfully provided samples independent of alcohol content. Groups were not masked as awareness of group contingencies was an essential intervention component.

RESULTS

The primary outcome of the intent-to-treat analyses (analyzed n = 40) was percent days abstinent as measured by the remote breathalyzer samples. Abstinence rates in the contingent group were 85%, which was significantly higher than the 38% recorded in the noncontingent group, corresponding to an odds ratio of 9.4 (95% CI = 4.0 to 22.2). Breathalyzer collection adherence rates were over 95%, and participant ratings of acceptability were also high.

CONCLUSIONS

These results support the efficacy, acceptability, and feasibility of this remotely deliverable abstinence reinforcement incentive intervention for the initiation and near-term maintenance of abstinence from alcohol in adults with alcohol use disorder. Due to low provider and participant burden, this procedure has the potential for broad dissemination.

摘要

背景

基于验证性禁欲发放货币奖励是治疗酒精使用障碍的有效方法。然而,由于缺乏准确、频繁地验证酒精禁欲的技术手段,这种技术的推广受到了限制。

方法

在本项随机平行试验中,我们使用了一种呼气酒精分析仪,它可以远程采集用户自行验证的呼气样本,通过短信和可充值借记卡为远程发放奖励提供便利,从而评估一种无需当面接触即可实施的酒精使用障碍的行为矫正治疗方法。我们从社区招募了患有酒精使用障碍的参与者(n=40),并将他们随机分配到有条件组或无条件组(每组 n=20)。有条件组每天远程提供阴性呼气酒精样本时,几乎可以立即获得金钱奖励。无条件组每天成功提供样本时,无论其酒精含量如何,都可以获得等额的金钱支付。两组均未设盲,因为了解组间条件是干预的重要组成部分。

结果

意向治疗分析(分析 n=40)的主要结果是通过远程呼气酒精分析仪测量的禁欲天数比例。有条件组的禁欲率为 85%,明显高于无条件组的 38%,这对应于 9.4 的优势比(95%置信区间为 4.0 至 22.2)。呼气酒精分析仪采集的依从率超过 95%,参与者对该方法的接受度也很高。

结论

这些结果支持这种远程提供的禁欲强化激励干预措施的有效性、可接受性和可行性,可用于启动和近期维持患有酒精使用障碍的成年人的酒精禁欲。由于提供者和参与者的负担较低,该程序具有广泛推广的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f50e/6518919/7eb54dfa9a0b/ACER-42-2423-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验