School of Sport, Exercise, and Health Sciences, Loughborough University , Loughborough , United Kingdom.
J Appl Physiol (1985). 2019 Jan 1;126(1):51-59. doi: 10.1152/japplphysiol.01082.2017. Epub 2018 Oct 18.
Sprint interval training (SIT) combined with postexercise blood flow restriction (BFR) is a novel method to increase maximal oxygen uptake (V̇o) in trained individuals and also provides a potent acute stimulus for angiogenesis and mitochondrial biogenesis. The efficacy to enhance endurance performance, however, has yet to be demonstrated. Trained male cyclists ( n = 21) (V̇o: 62.8 ± 3.7 ml·min·kg) undertook 4 wk of SIT (repeated 30-s maximal sprints) either alone (CON; n = 10) or with postexercise BFR ( n = 11). Before and after training V̇o, critical power (CP) and curvature constant ( W') were determined and muscle biopsies obtained for determination of skeletal muscle capillarity and mitochondrial protein content. CP increased ( P = 0.001) by a similar extent following CON (287 ± 39 W to 297 ± 43 W) and BFR (296 ± 40 W to 306 ± 36 W). V̇o increased following BFR by 5.9% ( P = 0.02) but was unchanged after CON ( P = 0.56). All markers of skeletal muscle capillarity and mitochondrial protein content were unchanged following either training intervention. In conclusion, 4 wk of SIT increased CP; however, this was not enhanced further with BFR. SIT was not sufficient to elicit changes in skeletal muscle capillarity and mitochondrial protein content with or without BFR. However, we further demonstrate the potency of combining BFR with SIT to enhance V̇o in trained individuals. NEW & NOTEWORTHY This investigation has demonstrated that 4 wk of sprint interval training (SIT) increased critical power in trained individuals; however, postexercise blood flow restriction (BFR) did not enhance this further. SIT, with or without BFR, did not induce any changes in skeletal muscle capillarity or mitochondrial protein content in our trained population. We do, however, confirm previous findings that SIT combined with BFR is a potent stimulus to enhance maximal oxygen uptake.
冲刺间歇训练（SIT）结合运动后血流限制（BFR）是一种提高训练有素个体最大摄氧量（V̇o）的新方法，同时也为血管生成和线粒体生物发生提供了强烈的急性刺激。然而，其提高耐力表现的效果尚未得到证实。21 名训练有素的男性自行车运动员（V̇o：62.8±3.7 ml·min·kg）进行了 4 周的 SIT（重复 30 秒最大冲刺），分别单独进行（CON；n=10）或在运动后进行 BFR（n=11）。在训练前后，测定了 V̇o、临界功率（CP）和曲率常数（W'），并获取肌肉活检以确定骨骼肌毛细血管密度和线粒体蛋白含量。CON 后 CP 增加（P=0.001），增加了 287±39 W 至 297±43 W，BFR 后增加了 296±40 W 至 306±36 W。BFR 后 V̇o 增加了 5.9%（P=0.02），但 CON 后无变化（P=0.56）。在两种训练干预后，所有骨骼肌毛细血管密度和线粒体蛋白含量的标志物均无变化。总之，4 周的 SIT 增加了 CP；然而，BFR 并不能进一步增强它。SIT 不足以引起或不引起 BFR 有或没有 BFR 的骨骼肌毛细血管密度和线粒体蛋白含量的变化。然而，我们进一步证明了将 BFR 与 SIT 结合以提高训练有素个体的 V̇o 的效力。新内容和值得注意的地方：本研究表明，4 周的冲刺间歇训练（SIT）可提高训练有素个体的临界功率；然而，运动后血流限制（BFR）并不能进一步提高这一功率。在我们的训练人群中，SIT，无论是否结合 BFR，都不会引起骨骼肌毛细血管密度或线粒体蛋白含量的任何变化。然而，我们确实证实了之前的发现，即 SIT 与 BFR 结合是提高最大摄氧量的有力刺激。
