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脑肠轴：临床意义。

Brain-Gut Axis: Clinical Implications.

机构信息

Department of Pediatrics, Columbia University College of Physicians and Surgeons, 630 West 168th Street, PH 17, New York, NY 10032, USA.

Department of Pediatrics, Columbia University College of Physicians and Surgeons, 630 West 168th Street, PH 17, New York, NY 10032, USA.

出版信息

Gastroenterol Clin North Am. 2018 Dec;47(4):727-739. doi: 10.1016/j.gtc.2018.07.002. Epub 2018 Sep 28.

DOI:10.1016/j.gtc.2018.07.002
PMID:30337029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6829582/
Abstract

This article provides an overarching view of what is currently known about the physiology of the brain-gut axis in both health and disease and how these concepts apply to irritable bowel syndrome, the most common functional gastrointestinal disorder in pediatrics.

摘要

本文概述了目前已知的健康和疾病状态下脑肠轴生理学的知识，以及这些概念如何适用于儿科最常见的功能性胃肠疾病——肠易激综合征。

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[2]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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[2]
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[3]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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本文引用的文献

[1]
Neurostimulation for abdominal pain-related functional gastrointestinal disorders in adolescents: a randomised, double-blind, sham-controlled trial.

Lancet Gastroenterol Hepatol. 2017-8-18

[2]
A Diet Low in Fermentable Oligo-, Di-, and Monosaccharides and Polyols Improves Quality of Life and Reduces Activity Impairment in Patients With Irritable Bowel Syndrome and Diarrhea.

Clin Gastroenterol Hepatol. 2017-6-28

[3]
The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS.

Gut. 2017-6-7

[4]
Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome.

Gastroenterology. 2017-5-5

[5]
Early adverse life events are associated with altered brain network architecture in a sex- dependent manner.

Neurobiol Stress. 2017-2-17

[6]
Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials.

Nutr Res. 2016-9

[7]
Pilot Study of Functional Magnetic Resonance Imaging Responses to Somatic Pain Stimuli in Youth With Functional and Inflammatory Gastrointestinal Disease.

J Pediatr Gastroenterol Nutr. 2016-11

[8]
The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System.

Gastroenterology. 2016-11

[9]
Neurotransmitters: The Critical Modulators Regulating Gut-Brain Axis.

J Cell Physiol. 2017-9

[10]
Intestinal microbiota and chronic constipation.

Springerplus. 2016-7-19

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