Department of Electrical Engineering, Indian Institute of Technology Patna, Bihta 801103, India.
Comput Methods Programs Biomed. 2018 Oct;165:175-186. doi: 10.1016/j.cmpb.2018.08.008. Epub 2018 Aug 22.
Cardiovascular diseases (CVDs) are the leading cause of deaths worldwide. Due to an increase in the rate of global mortalities, biopathological signal processing and evaluation are widely used in the ambulatory situations for healthcare applications. For decades, the processing of pathological electrocardiogram (ECG) signals for arrhythmia detection has been thoroughly studied for diagnosis of various cardiovascular diseases. Apart from these studies, efficient diagnosis of ECG signals remains a challenge in the clinical cardiovascular domain due to its non-stationary nature. The classical signal processing methods are widely employed to analyze the ECG signals, but they exhibit certain limitations and hence, are insufficient to achieve higher accuracy.
This study presents a novel technique for an efficient representation of electrocardiogram (ECG) signals using sparse decomposition using composite dictionary (CD). The dictionary consists of the stockwell, sine and cosine analytical functions. The technique decomposes an input ECG signal into stationary and non-stationary components or atoms. For each of these atoms, five features i.e., permutation entropy, energy, RR-interval, standard deviation and kurtosis are extracted to determine the feature sets representing the heartbeats that are classified into different categories using the multi-class least-square twin support vector machines. The artificial bee colony (ABC) technique is used to determine the optimal classifier parameters. The proposed method is evaluated under category and personalized schemes and its validation is performed on MIT-BIH data.
The experimental results reported a higher overall accuracy of 99.21% and 90.08% in category and personalized schemes respectively than the existing techniques reported in the literature. Further a sensitivity, positive predictivity and F-score of 99.21% each in the category based scheme and 90.08% each in the personalized schemes respectively.
The proposed methodology can be utilized in computerized decision support systems to monitor different classes of cardiac arrhythmias with higher accuracy for early detection and treatment of cardiovascular diseases.
心血管疾病(CVDs)是全球死亡的主要原因。由于全球死亡率的增加,生物病理信号处理和评估在医疗保健应用的动态环境中得到了广泛应用。几十年来,为了诊断各种心血管疾病,对病理性心电图(ECG)信号的处理进行了深入研究以检测心律失常。除了这些研究之外,由于其非平稳性质,心电图信号的有效诊断仍然是临床心血管领域的一个挑战。经典的信号处理方法广泛用于分析心电图信号,但它们存在某些局限性,因此不足以实现更高的准确性。
本研究提出了一种使用复合字典(CD)的稀疏分解来有效地表示心电图(ECG)信号的新技术。字典由斯托克韦尔、正弦和余弦解析函数组成。该技术将输入的心电图信号分解为平稳和非平稳分量或原子。对于每个原子,提取五个特征,即排列熵、能量、RR 间隔、标准差和峰度,以确定表示使用多类最小二乘孪生支持向量机分类为不同类别的心跳的特征集。人工蜂群(ABC)技术用于确定最佳分类器参数。该方法在类别和个性化方案下进行评估,并在 MIT-BIH 数据上进行验证。
实验结果报告了更高的整体准确性,在类别方案中为 99.21%,在个性化方案中为 90.08%,优于文献中报道的现有技术。此外,类别方案中的灵敏度、阳性预测值和 F 分数分别为 99.21%,个性化方案中的灵敏度、阳性预测值和 F 分数分别为 90.08%。
所提出的方法可用于计算机化决策支持系统,以更高的准确性监测不同类型的心律失常,从而早期发现和治疗心血管疾病。