Department of Statistics and Operations Research, Universidad de Valladolid, Valladolid, Spain.
Sci Rep. 2021 Feb 12;11(1):3724. doi: 10.1038/s41598-021-82520-w.
A novel approach for analysing cardiac rhythm data is presented in this paper. Heartbeats are decomposed into the five fundamental P, Q, R, S and T waves plus an error term to account for artifacts in the data which provides a meaningful, physical interpretation of the heart's electric system. The morphology of each wave is concisely described using four parameters that allow all the different patterns in heartbeats to be characterized and thus differentiated This multi-purpose approach solves such questions as the extraction of interpretable features, the detection of the fiducial marks of the fundamental waves, or the generation of synthetic data and the denoising of signals. Yet the greatest benefit from this new discovery will be the automatic diagnosis of heart anomalies as well as other clinical uses with great advantages compared to the rigid, vulnerable and black box machine learning procedures, widely used in medical devices. The paper shows the enormous potential of the method in practice; specifically, the capability to discriminate subjects, characterize morphologies and detect the fiducial marks (reference points) are validated numerically using simulated and real data, thus proving that it outperforms its competitors.
本文提出了一种分析心拍数据的新方法。心拍被分解为五个基本的 P、Q、R、S 和 T 波加上一个误差项,以解释数据中的伪影,为心脏的电系统提供了有意义的物理解释。使用四个参数简洁地描述每个波的形态,允许对所有不同的心拍模式进行特征化和区分。这种多用途的方法解决了提取可解释特征、检测基本波的基准标记、生成合成数据和对信号进行去噪等问题。然而,这一新发现的最大好处将是自动诊断心脏异常以及其他临床用途,与广泛应用于医疗设备的刚性、脆弱和黑盒机器学习过程相比具有巨大的优势。本文展示了该方法在实践中的巨大潜力;具体来说,使用模拟和真实数据进行数值验证,证明了该方法能够区分对象、描述形态和检测基准标记(参考点),性能优于竞争对手。