通过波前整形增加光学相干断层扫描穿透深度的时域有限差分分析
Finite-difference time-domain analysis of increased penetration depth in optical coherence tomography by wavefront shaping.
作者信息
Kim Jong Uk, Choi Hyun, Park YongKeun, Shin Jonghwa
机构信息
Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
Department of Mechanical Engineering, Konyang University, Nonsan, Chungcheongnam 32992, South Korea.
出版信息
Biomed Opt Express. 2018 Jul 26;9(8):3883-3897. doi: 10.1364/BOE.9.003883. eCollection 2018 Aug 1.
Abstract
Multiple scattering in turbid media inhibits optimal light focusing and thus limits the penetration depth in optical coherence tomography (OCT). However, the effects of multiple scattering in a turbid medium can be systematically controlled by shaping the incident wavefront. The authors utilize the reciprocity of Maxwell's equations and finite-difference time-domain numerical analysis to investigate the ultimate performance bounds of wavefront shaping-OCT under ideal and realistic configurations and compare them with the conventional method. The results reveal that the optimized impinging wavefront significantly enhances the penetration depth of OCT.
摘要
浑浊介质中的多次散射会抑制最佳光聚焦，从而限制光学相干断层扫描（OCT）的穿透深度。然而，通过塑造入射波前，可以系统地控制浑浊介质中多次散射的影响。作者利用麦克斯韦方程组的互易性和时域有限差分数值分析，研究了在理想和实际配置下波前整形-OCT的极限性能边界，并将其与传统方法进行比较。结果表明，优化后的入射波前显著提高了OCT的穿透深度。
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