Aleisa Abdullah, Lim Yeun, Gordon Samantha, Her Min Ji, Zancanaro Pedro, Abudu Minawaer, Deverapalli Sandhya Chowdary, Madani Abdulaziz, Rosmarin David
Department of Dermatology, Tufts Medical Center, Boston, Massachusetts.
Tufts School of Medicine, Tufts University, Boston, Massachusetts.
Pediatr Dermatol. 2019 Jan;36(1):e44-e45. doi: 10.1111/pde.13699. Epub 2018 Oct 18.
Alopecia areata (AA) is relatively common and can have a significant impact on quality of life, especially in a pediatric population. Currently available treatments are often ineffective or have poor safety profiles. Recent studies have highlighted the importance of the Th1 pathway in the pathogenesis of AA, suggesting ustekinumab as a treatment modality for this disease. We present three pediatric AA patients who demonstrated hair regrowth after initiating ustekinumab.
斑秃（AA）相对常见，会对生活质量产生重大影响，尤其是在儿童群体中。目前可用的治疗方法往往无效或安全性不佳。最近的研究强调了Th1途径在斑秃发病机制中的重要性，提示乌司奴单抗可作为该疾病的一种治疗方式。我们报告了三名儿童斑秃患者，他们在开始使用乌司奴单抗后出现了毛发再生。
