[T- and B-lymphocytes in lymphogranulomatosis].

The authors report the results of the complex investigation of T-and B-lymphocytes in peripheral blood and functional features of T-cells in the reaction of blasttransformation with PHA in 27 patients with lymphogranulomatosis and in 30 healthy individuals. Generalized forms of lymphogranulomatosis of stage III-IV (in 21 of 27 patients) were predominating. All patients showed an active phase of the lesion. T-system immunity was found to be suppressed, that was manifested in reduced T-cells number, a decreased lymphocytes RBT to PHA per one or two dilutions. It is supposed that the observed T-lymphocytes disorders is one of the causes of the impairment of cell immunity reactions, found in vivo in patients with lymphogranulomatosis.