Yalcin Eda Didem, Koparal Mahmut, Aksoy Orhan
Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Gaziantep University, Sehitkamil, 27410, Gaziantep, Turkey.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Merkez, 02200, Adiyaman, Turkey.
Eur Arch Otorhinolaryngol. 2018 Dec;275(12):2991-2996. doi: 10.1007/s00405-018-5177-z. Epub 2018 Oct 20.
Ectodermal dysplasia (ED) is a congenital syndrome characterized by abnormal development of ectodermal structures, such as skin, hair, nails, teeth, or salivary glands. Patients with ED demonstrate craniofacial dysmorphology, midfacial hypoplasia and hypodontia. The aim of this study is to evaluate volume and surface area of maxillary sinus and craniofacial structures in patients with ectodermal dysplasia (ED) using cone-beam computed tomography (CBCT) images.
The CBCT images of 20 patients with ED (study group) and 20 healthy individuals (control) which are equal in terms of age and gender were evaluated. After a three-dimensional analysis and segmentation of each maxillary sinus, the volume and surface area were calculated. Craniofacial dimensions were measured on the sagittal planes of the CBCT images. The results of the ED and control groups were statistically compared.
The right and left sinus volumes and surface areas were significantly lower in the ED group than in the control group (p < 0.05) while the SNA was significantly higher (p < 0.05). ANB and SN-GoMe were also lower in patients with ED than in controls (p < 0.05). The difference in SNB values between the two groups was not significant (p > 0.05).
The volumes and surface areas of both maxillary sinuses were found to be smaller in patients with ED compared to healthy individuals. Class III malocclusion with maxillary retrusion is a characteristic craniofacial feature of these patients.
外胚层发育不良（ED）是一种先天性综合征，其特征为外胚层结构（如皮肤、毛发、指甲、牙齿或唾液腺）发育异常。ED患者表现出颅面畸形、面中部发育不全和牙齿发育不全。本研究的目的是使用锥形束计算机断层扫描（CBCT）图像评估外胚层发育不良（ED）患者上颌窦及颅面结构的体积和表面积。
评估20例ED患者（研究组）和20名年龄及性别匹配的健康个体（对照组）的CBCT图像。对每个上颌窦进行三维分析和分割后，计算其体积和表面积。在CBCT图像的矢状面上测量颅面尺寸。对ED组和对照组的结果进行统计学比较。
ED组左右鼻窦的体积和表面积均显著低于对照组（p < 0.05），而SNA显著高于对照组（p < 0.05）。ED患者的ANB和SN - GoMe也低于对照组（p < 0.05）。两组间SNB值的差异无统计学意义（p > 0.05）。
与健康个体相比，发现ED患者双侧上颌窦的体积和表面积较小。上颌后缩的III类错牙合是这些患者的典型颅面特征。
