Korovesis Theofanis, Katritsis George, Koudounis Panagiotis, Zografos Theodoros
First Faculty of Medicine, Charles University, Glyfada, Greece.
Department of Cardiology, Imperial College London, London, UK.
BMJ Case Rep. 2018 Oct 21;2018:bcr-2018-226813. doi: 10.1136/bcr-2018-226813.
Coronary artery ectasia (CAE) can be ascribed, in the majority of cases, to coronary atherosclerosis. Nevertheless, the presence of isolated ectatic lesions without obstructive coronary artery disease and the association of CAE with several autoimmune diseases characterised by systemic vascular involvement suggest that the pathogenesis of CAE may extend beyond coronary atherosclerosis. We herein report the case of a 56-year-old male patient with Crohn's disease and isolated CAE, who has been found positive for IgM and IgA antiendothelial cell antibodies, and discuss a potential pathogenic mechanism.
冠状动脉扩张（CAE）在大多数情况下可归因于冠状动脉粥样硬化。然而，存在无阻塞性冠状动脉疾病的孤立性扩张病变以及CAE与几种以系统性血管受累为特征的自身免疫性疾病的关联表明，CAE的发病机制可能超出冠状动脉粥样硬化的范畴。我们在此报告一例56岁患有克罗恩病和孤立性CAE的男性患者，其IgM和IgA抗内皮细胞抗体检测呈阳性，并探讨一种潜在的致病机制。
