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腹腔镜辅助手助肾上腺切除术治疗大于 5cm 的肿瘤。

Laparoscopic hand-assisted adrenalectomy for tumours larger than 5 cm.

机构信息

Departments of Transplant and Endocrine Surgery, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

出版信息

Clin Endocrinol (Oxf). 2019 Jan;90(1):74-78. doi: 10.1111/cen.13883. Epub 2018 Nov 15.

Abstract

OBJECTIVE

Adrenal surgery remains a distinct surgical challenge. Technical challenges associated with laparoscopic adrenalectomy are tumour size, haemorrhage control and oncological compromise. Hand-assisted laparoscopic (HAL) adrenalectomy, utilizing a hand-port device, offers minimally invasive surgery with the advantages and safety of tactile feedback. We aimed to assess the efficacy of HAL for patients requiring adrenalectomy for tumours over 5 cm in size.

CONTEXT

Hand-assisted laparoscopic surgery is used in several surgical specialities over totally laparoscopic surgery to manage sizeable pathology, reduce operating time and conversion rates. HAL adrenalectomy is demonstrated in this series as a safe alternative to laparoscopic adrenalectomy for large adrenal tumours.

DESIGN

A retrospective analysis of all HAL adrenalectomies performed over 8 years (October 2006-May 2015) by a single surgeon was performed. This case series is the largest study of this technique.

PATIENTS

All patients who were fit for surgery with adrenal tumours (over 5 cm) were included.

ANALYSIS

Primary endpoints were overall mortality, operating time, hospital stay, complications and conversion to open surgery.

RESULTS

A total of 56 patients underwent the procedure. A total of 43 had unilateral and 13 bilateral lesions. Most lesions (45) were histologically benign. These included functioning and non-functioning tumours. Median tumour size was 8 cm (range 5-19 cm). There was one (1.8%) intra-operative conversion and no peri-operative mortality. Postoperative complications occurred in 8 (14%) patients, all self-limiting. The median length of stay was 6 days (range 2-21). There was one recurrence of pathology with repeat surgery.

CONCLUSION

Hand-assisted laparoscopic surgery offers a safe reproducible approach to adrenal surgery combining minimally invasive surgery with tactile integration. Although previously described in small numbers, this represents the largest case series to date. HAL is a safe minimally invasive surgical option for larger tumours, including malignancies. The HAL technique may additionally offer a shorter learning curve for trainee adrenal surgeons.

摘要

目的

肾上腺手术仍然是一项独特的外科挑战。腹腔镜肾上腺切除术的技术挑战与肿瘤大小、出血控制和肿瘤学损害有关。手助腹腔镜(HAL)肾上腺切除术利用手端口设备提供微创外科手术,具有触觉反馈的优势和安全性。我们旨在评估 HAL 在手助腹腔镜手术中用于治疗 5cm 以上肿瘤的疗效。

背景

手助腹腔镜手术在几个外科专业中用于治疗较大的病理,以减少手术时间和转化率。在这个系列中,HAL 肾上腺切除术被证明是腹腔镜肾上腺切除术治疗大型肾上腺肿瘤的安全替代方法。

设计

对一位外科医生在 8 年内(2006 年 10 月至 2015 年 5 月)进行的所有 HAL 肾上腺切除术进行了回顾性分析。这是该技术的最大研究系列。

患者

所有适合手术的肾上腺肿瘤(超过 5cm)患者均纳入研究。

分析

主要终点是总死亡率、手术时间、住院时间、并发症和转为开放手术。

结果

共有 56 例患者接受了该手术。单侧病变 43 例,双侧病变 13 例。大多数病变(45 例)为组织学良性,包括功能性和非功能性肿瘤。肿瘤大小中位数为 8cm(范围 5-19cm)。有 1 例(1.8%)术中转换,无围手术期死亡。术后并发症发生在 8 例(14%)患者中,均为自限性。中位住院时间为 6 天(范围 2-21 天)。有 1 例再次手术切除。

结论

手助腹腔镜手术为肾上腺手术提供了一种安全、可重复的方法,将微创外科手术与触觉整合相结合。尽管之前描述的数量较少,但这是迄今为止最大的病例系列。HAL 是一种安全的微创手术选择,适用于包括恶性肿瘤在内的较大肿瘤。HAL 技术可能还为接受培训的肾上腺外科医生提供了更短的学习曲线。

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