Driver Sangeeta, Stork Ryan
NeuroRehabilitation. 2018;43(3):347-353. doi: 10.3233/NRE-182536.
Sleep-wake disturbances (SWD) are prevalent in the traumatic brain injury (TBI) population and may exacerbate related neurobehavioral impairments. As such, it is important to recognize and treat SWD early to allow for optimal cognitive recovery following a TBI. A number of medications are currently available for treatment of SWD. However, most research in this area has historically focused on neurologically intact populations. This article reviews key pharmacologic treatment principles and agents to consider for use in the treatment of TBI-related SWD. In addition, it highlights available research literature that has examined the use of sleep medications in this unique population.
睡眠-觉醒障碍（SWD）在创伤性脑损伤（TBI）人群中很常见，并且可能会加重相关的神经行为损伤。因此，早期识别和治疗SWD对于TBI后实现最佳认知恢复很重要。目前有多种药物可用于治疗SWD。然而，该领域的大多数研究历来都集中在神经功能正常的人群上。本文综述了用于治疗TBI相关SWD的关键药物治疗原则和药物。此外，还强调了研究该特殊人群使用睡眠药物的现有文献。
