Do Toll-like Receptors Play a New Role as a Biomarker of Irritable Bowel Syndrome?

Suppr

超能文献

作者信息

Kim Hyun Jin

机构信息

Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Gyeongsangnam-do, Korea.

出版信息

J Neurogastroenterol Motil. 2018 Oct 1;24(4):510-511. doi: 10.5056/jnm18153.

DOI:10.5056/jnm18153

PMID:30347933

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6175550/

Abstract

摘要

相似文献

Do Toll-like Receptors Play a New Role as a Biomarker of Irritable Bowel Syndrome?

J Neurogastroenterol Motil. 2018 Oct 1;24(4):510-511. doi: 10.5056/jnm18153.

Increased Expression of Toll-Like Receptors 4, 5, and 9 in Small Bowel Mucosa from Patients with Irritable Bowel Syndrome.肠易激综合征患者小肠黏膜中Toll样受体4、5和9的表达增加

Biomed Res Int. 2017;2017:9624702. doi: 10.1155/2017/9624702. Epub 2017 Jan 29.

Differential expression of toll-like receptors in patients with irritable bowel syndrome.肠易激综合征患者中 toll 样受体的差异表达。

Am J Gastroenterol. 2011 Feb;106(2):329-36. doi: 10.1038/ajg.2010.438. Epub 2010 Nov 23.

Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: future therapeutic targets.炎症性肠病和肠易激综合征中的神经免疫相互作用：未来的治疗靶点。

Eur J Pharmacol. 2008 May 13;585(2-3):361-74. doi: 10.1016/j.ejphar.2008.02.095. Epub 2008 Mar 18.

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal.靶向组胺受体治疗肠易激综合征：批判性评估

J Neurogastroenterol Motil. 2017 Jul 30;23(3):341-348. doi: 10.5056/jnm16203.

Altered peripheral toll-like receptor responses in the irritable bowel syndrome.肠易激综合征中外周 toll 样受体反应的改变。

Aliment Pharmacol Ther. 2011 May;33(9):1045-52. doi: 10.1111/j.1365-2036.2011.04624.x. Epub 2011 Mar 9.

[The correlation study between the changes of intestinal mucosa predominant bacteria and Toll-like receptor 2, Toll-like receptor 4 gene expressions in diarrhea-predominant irritable bowel syndrome patients].腹泻型肠易激综合征患者肠道黏膜优势菌变化与Toll样受体2、Toll样受体4基因表达的相关性研究

Zhonghua Nei Ke Za Zhi. 2016 Jul 1;55(7):541-3. doi: 10.3760/cma.j.issn.0578-1426.2016.07.011.

Therapy of the postinfectious irritable bowel syndrome: an update.感染后肠易激综合征的治疗：最新进展

Clujul Med. 2017;90(2):133-138. doi: 10.15386/cjmed-752. Epub 2017 Apr 25.

A randomized, double-blind, placebo-controlled clinical trial of the effectiveness of the novel serotonin type 3 receptor antagonist ramosetron in both male and female Japanese patients with diarrhea-predominant irritable bowel syndrome.新型5-羟色胺3型受体拮抗剂雷莫司琼对日本腹泻型肠易激综合征男女患者有效性的随机、双盲、安慰剂对照临床试验。

Scand J Gastroenterol. 2008;43(10):1202-11. doi: 10.1080/00365520802240255.

Role of toll like receptors in irritable bowel syndrome: differential mucosal immune activation according to the disease subtype.Toll 样受体在肠易激综合征中的作用：根据疾病亚型的不同，黏膜免疫激活存在差异。

PLoS One. 2012;7(8):e42777. doi: 10.1371/journal.pone.0042777. Epub 2012 Aug 17.

引用本文的文献

Melatonin alleviates diarrhea and visceral hypersensitivity in rats with diarrhea-predominant irritable bowel syndrome by modulating of the TLR4/MyD88/NF-κB pathway.

BMC Gastroenterol. 2025 Oct 9;25(1):715. doi: 10.1186/s12876-025-04203-4.

Crosstalk Between Intestinal Serotonergic System and Pattern Recognition Receptors on the Microbiota-Gut-Brain Axis.肠内 5-羟色胺能系统与肠道菌群-肠-脑轴上模式识别受体的串扰。

Front Endocrinol (Lausanne). 2021 Nov 8;12:748254. doi: 10.3389/fendo.2021.748254. eCollection 2021.

Kynurenine Pathway of Tryptophan Metabolism in Migraine and Functional Gastrointestinal Disorders.色氨酸代谢的犬尿氨酸途径与偏头痛和功能性胃肠疾病。

Int J Mol Sci. 2021 Sep 20;22(18):10134. doi: 10.3390/ijms221810134.

Modified Renshen Wumei Decoction Alleviates Intestinal Barrier Destruction in Rats with Diarrhea.加味人参乌梅汤减轻腹泻模型大鼠肠黏膜屏障损伤

J Microbiol Biotechnol. 2021 Sep 28;31(9):1295-1304. doi: 10.4014/jmb.2106.06037.

本文引用的文献

Expression of Toll-like Receptors, Pro-, and Anti-inflammatory Cytokines in Relation to Gut Microbiota in Irritable Bowel Syndrome: The Evidence for Its Micro-organic Basis.肠易激综合征中Toll样受体、促炎和抗炎细胞因子表达与肠道微生物群的关系：其微生物学基础的证据

J Neurogastroenterol Motil. 2018 Oct 1;24(4):628-642. doi: 10.5056/jnm18130.

Irritable bowel syndrome: a clinical review.肠易激综合征：临床综述。

JAMA. 2015 Mar 3;313(9):949-58. doi: 10.1001/jama.2015.0954.

From cytokines to toll-like receptors and beyond - current knowledge and future research needs in irritable bowel syndrome.从细胞因子到 toll 样受体及其他——肠易激综合征的现有知识和未来研究需求。

J Neurogastroenterol Motil. 2010 Oct;16(4):363-73. doi: 10.5056/jnm.2010.16.4.363. Epub 2010 Oct 30.

T-cell activation in patients with irritable bowel syndrome.肠易激综合征患者的T细胞活化

Am J Gastroenterol. 2009 May;104(5):1205-12. doi: 10.1038/ajg.2009.116. Epub 2009 Apr 14.

Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptoms.肠易激综合征中的黏膜免疫激活：性别依赖性及其与消化症状的关联

Am J Gastroenterol. 2009 Feb;104(2):392-400. doi: 10.1038/ajg.2008.94. Epub 2009 Jan 13.

The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects.肠易激综合征患者的粪便微生物群与健康受试者的粪便微生物群有显著差异。

Gastroenterology. 2007 Jul;133(1):24-33. doi: 10.1053/j.gastro.2007.04.005. Epub 2007 Apr 14.

Intestinal permeability and irritable bowel syndrome.肠道通透性与肠易激综合征

Neurogastroenterol Motil. 2007 Jul;19(7):545-52. doi: 10.1111/j.1365-2982.2007.00925.x.

Functional bowel disorders.功能性肠病

Gastroenterology. 2006 Apr;130(5):1480-91. doi: 10.1053/j.gastro.2005.11.061.

A role for inflammation in irritable bowel syndrome?炎症在肠易激综合征中起作用吗？

Gut. 2002 Jul;51 Suppl 1(Suppl 1):i41-4. doi: 10.1136/gut.51.suppl_1.i41.

Toll-like receptors and innate immunity.Toll样受体与天然免疫

Nat Rev Immunol. 2001 Nov;1(2):135-45. doi: 10.1038/35100529.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验