直肠癌患者根治性切除术后良性小肠梗阻的危险因素。
The risk factors for benign small bowel obstruction following curative resection in patients with rectal cancer.
机构信息
Department of Colorectal Cancer, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Huanhuxi Road, Hexi District, Tianjin, People's Republic of China.
出版信息
World J Surg Oncol. 2018 Oct 22;16(1):212. doi: 10.1186/s12957-018-1510-7.
BACKGROUND
So far there have been limited studies about the risk factors for benign small bowel obstruction (SBO) after colorectal cancer surgery. This study aimed to determine the factors affecting the development of benign SBO following curative resection in patients with rectal cancer.
METHODS
Patients (3472) receiving curative resection of rectal cancer at the Department of Colorectal Cancer, Tianjin Medical University Cancer Institute and Hospital, between January 2003 and December 2012 were retrospectively studied. The incidence of benign SBO and its risk factors were then determined.
RESULTS
The incidence of benign SBO was 7.3% (253/3472) in follow-up studies with an average time of 68 months. Further, 27% (68/253) of the patients received operative treatment because of the signs of strangulation or the lack of clinical improvement with conservative management. Open surgery and radiotherapy were defined as the risk factors for benign SBO after curative resection in patients with rectal cancer (P < 0.001).
CONCLUSION
Open surgery plus radiotherapy led to an increased risk of benign SBO in rectal cancer patients receiving curative resection.
背景
目前为止，关于结直肠癌手术后发生良性小肠梗阻（SBO）的危险因素的研究有限。本研究旨在确定影响直肠癌根治性切除术后良性 SBO 发展的因素。
方法
回顾性研究 2003 年 1 月至 2012 年 12 月在天津医科大学肿瘤医院结直肠肿瘤科接受直肠癌根治性切除术的患者（3472 例）。然后确定良性 SBO 的发生率及其危险因素。
结果
在平均 68 个月的随访研究中，良性 SBO 的发生率为 7.3%（253/3472）。进一步的，由于有绞窄的迹象或保守治疗后临床症状没有改善，27%（68/253）的患者接受了手术治疗。开放性手术和放疗被定义为直肠癌根治性切除术后发生良性 SBO 的危险因素（P < 0.001）。
结论
开放性手术加放疗导致接受根治性切除术的直肠癌患者发生良性 SBO 的风险增加。
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