Yang Kwan Mo, Yu Chang Sik, Lee Jong Lyul, Kim Chan Wook, Yoon Yong Sik, Park In Ja, Lim Seok-Byung, Kim Jin Cheon
Division of Colon and Rectal Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Medicine (Baltimore). 2017 Oct;96(43):e8316. doi: 10.1097/MD.0000000000008316.
An adhesive small bowel obstruction (ASBO) is generally caused by postoperative adhesions and is more frequently associated with colorectal surgeries than other procedures. We compared the outcomes of operative and conservative management of ASBO after primary colorectal cancer surgery.We retrospectively reviewed 5060 patients who underwent curative surgery for primary colorectal cancer; 388 of these patients (7.7%) were readmitted with a diagnosis of SBO. We analyzed the clinical course of these patients with reference to the cause of their surgery.Of the 388 SBO patients analyzed, 170 were diagnosed with ASBO. Their 3-, 5-, and 7-year recurrence-free survival rates were 86.1%, 72.8%, and 61.5%, respectively. The median follow-up period was 59.2 months. Repeated conservative management for ASBO without surgical management led to higher recurrence rates: 21.0% after the first admission, 41.7% after the second, 60.0% after the third, and 100% after the fourth (P = .006). Surgical management was needed for 19.2%, 22.2%, 50%, and 66.7% of patients admitted with ASBO on the first to fourth hospitalizations, respectively. Repeated hospitalization for obstruction led to a greater possibility of surgical management (P = .001). Of 27 patients with surgical management at the first admission, 6 (17.6%) were readmitted with a diagnosis of SBO, but there were no further episodes of SBO in the surgically managed patients.Patients who undergo operative management for ASBO have a reduced risk of recurrence requiring hospitalization, whereas those with repeated conservative management have an increased risk of recurrence and require operative management. Operative management should be considered for recurrent SBO.
粘连性小肠梗阻(ASBO)通常由术后粘连引起,与结直肠手术相比,其在结直肠手术中更为常见。我们比较了原发性结直肠癌手术后ASBO的手术治疗和保守治疗效果。我们回顾性分析了5060例行原发性结直肠癌根治性手术的患者;其中388例(7.7%)因小肠梗阻再次入院。我们参照手术原因分析了这些患者的临床病程。在分析的388例小肠梗阻患者中,170例被诊断为ASBO。他们的3年、5年和7年无复发生存率分别为86.1%、72.8%和61.5%。中位随访期为59.2个月。ASBO患者未经手术而反复进行保守治疗会导致更高的复发率:首次入院后为21.0%,第二次为41.7%,第三次为60.0%,第四次为100%(P = 0.006)。首次至第四次因ASBO入院的患者分别有19.2%、22.2%、50%和66.7%需要手术治疗。因梗阻反复住院导致手术治疗的可能性更大(P = 0.001)。首次入院接受手术治疗的27例患者中,6例(17.6%)因小肠梗阻再次入院,但接受手术治疗的患者未再出现小肠梗阻发作。接受ASBO手术治疗的患者因复发需住院的风险降低,而反复接受保守治疗的患者复发风险增加且需要手术治疗。对于复发性小肠梗阻应考虑手术治疗。