Department of Applied Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Department of Applied Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Talanta. 2019 Jan 15;192:241-247. doi: 10.1016/j.talanta.2018.09.054. Epub 2018 Sep 18.
Residual chemicals on personal care and healthcare products, such as sanitary articles, sterile gauze bandages, nappies, plasters, were studied by direct analysis in real time mass spectrometry (DART-MS). We have identified around 40 compounds in seventeen different commercially available items. The tentative identification was further supported for about half of the chemicals by tandem mass spectrometric experiments (DART MS/MS). The most notable hazardous substances were tributyl phosphate, tris(2,4-di-tert-butylphenyl) phosphite, phthalic acid esters, erucamide, and nonylphenol ethoxylates (NPEs). In addition, we developed an efficient DART-MS analysis to determine the concentration of NPE in a swab sample. The quantitative result obtained by DART-MS was confirmed by liquid chromatography with mass spectrometric detection (LC-MS).
直接实时分析质谱法（DART-MS）研究了个人护理和保健产品（如卫生用品、无菌纱布绷带、尿布、膏药）上的残留化学物质。我们已经在十七种不同的市售产品中鉴定出约 40 种化合物。通过串联质谱实验（DART-MS/MS）对约一半的化学物质进行了初步鉴定。最显著的有害物质是磷酸三丁酯、三（2,4-二叔丁基苯基）亚磷酸酯、邻苯二甲酸酯、芥酰胺和壬基酚聚氧乙烯醚（NPE）。此外，我们开发了一种高效的 DART-MS 分析方法来测定棉签样品中 NPE 的浓度。通过 DART-MS 获得的定量结果通过液质联用（LC-MS）进行了确认。
