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Segmental rigidity and spinal myoclonus as a paraneoplastic syndrome.

作者信息

Roobol T H, Kazzaz B A, Vecht C J

出版信息

J Neurol Neurosurg Psychiatry. 1987 May;50(5):628-31. doi: 10.1136/jnnp.50.5.628.

DOI:10.1136/jnnp.50.5.628
PMID:3035105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1031977/
Abstract

A 68 year old woman is described with persisting muscular rigidity of the left lower leg together with transient myoclonic jerking in the left quadriceps muscle. Six weeks after onset a small cell carcinoma of the lung became manifest. With radiotherapy and chemotherapy complete remission was achieved. Segmental muscular spasm improved at the same time. Necropsy revealed loss and degeneration of alpha-motor neuron cells at one side of the anterior horn of the lumbar enlargement. This case may represent another manifestation of paraneoplastic subacute motor neuronopathy.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8c/1031977/01042288c4e0/jnnpsyc00552-0119-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8c/1031977/01042288c4e0/jnnpsyc00552-0119-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a8c/1031977/01042288c4e0/jnnpsyc00552-0119-a.jpg

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本文引用的文献

1
NEUROMUSCULAR DISORDERS ASSOCIATED WITH MALIGNANT NEOPLASTIC DISEASE.与恶性肿瘤相关的神经肌肉疾病
J Chronic Dis. 1963 Jul;16:777-95. doi: 10.1016/0021-9681(63)90011-0.
2
Muscle spasm and abnormal postures resulting from damage to interneurones in spinal cord.脊髓中间神经元受损导致的肌肉痉挛和异常姿势。
Arch Neurol. 1960 Nov;3:500-12. doi: 10.1001/archneur.1960.00450050020004.
3
Interneurones and rigidity of spinal origin.中间神经元与脊髓源性强直
前列腺癌中的腿部酒精反应性动作性肌阵挛：一种新型副肿瘤综合征？
Tremor Other Hyperkinet Mov (N Y). 2015 Dec 22;5:357. doi: 10.7916/D80G3JSX. eCollection 2015.
4
A review of the therapy of paraneoplastic neurologic syndromes.副肿瘤性神经系统综合征的治疗综述。
J Neurooncol. 1999 Jan;41(2):181-94. doi: 10.1023/a:1006133102928.
5
Review of 23 patients affected by the stiff man syndrome: clinical subdivision into stiff trunk (man) syndrome, stiff limb syndrome, and progressive encephalomyelitis with rigidity.对23例僵人综合征患者的回顾：临床分为僵躯干（人）综合征、僵肢综合征和进行性脑脊髓炎伴强直。
J Neurol Neurosurg Psychiatry. 1998 Nov;65(5):633-40. doi: 10.1136/jnnp.65.5.633.
6
The stiff leg syndrome.僵腿综合征
J Neurol Neurosurg Psychiatry. 1997 Jan;62(1):31-7. doi: 10.1136/jnnp.62.1.31.
7
Stiff muscles.肌肉僵硬。
J Neurol Neurosurg Psychiatry. 1993 Feb;56(2):121-4. doi: 10.1136/jnnp.56.2.121.
8
Progressive encephalomyelitis with rigidity: a case report with magnetic resonance imaging findings.进行性脑脊髓炎伴僵硬：一例报告及磁共振成像结果
J Neurol Neurosurg Psychiatry. 1989 Dec;52(12):1429-31. doi: 10.1136/jnnp.52.12.1429.
9
Autoimmune myastenia gravis with thymoma following the spontaneous remission of stiff-man syndrome.僵人综合征自发缓解后伴胸腺瘤的自身免疫性重症肌无力
Ital J Neurol Sci. 1990 Apr;11(2):177-80. doi: 10.1007/BF02335562.
10
Rigidity and painful muscle spasms in a patient with probable myelitis.
Ital J Neurol Sci. 1991 Dec;12(6):587-91. doi: 10.1007/BF02336956.
J Physiol. 1959 Jun 11;146(3):594-617. doi: 10.1113/jphysiol.1959.sp006214.
4
Newcastle disease encephalomyelitis in cats. II. Physiological studies on rhythmic myoclonus.猫新城疫脑脊髓炎。II. 节律性肌阵挛的生理学研究。
AMA Arch Neurol Psychiatry. 1959 Mar;81(3):285-91. doi: 10.1001/archneurpsyc.1959.02340150017002.
5
Spinal myoclonus with vacuolar degeneration of anterior horn cells.
Arch Neurol. 1980 Jul;37(7):451-3. doi: 10.1001/archneur.1980.00500560081014.
6
Rigidity in man due to spinal interneuron loss.
Arch Neurol. 1967 May;16(5):536-43. doi: 10.1001/archneur.1967.00470230088012.
7
Deafferentation to relieve spasticity or rigidity: reasons for failure in some cases of paraplegia.
J Neurosurg. 1966 Sep;25(3):270-4. doi: 10.3171/jns.1966.25.3.0270.
8
Synaptic potentials in hypoglossal motoneurones.舌下运动神经元的突触电位
J Physiol. 1965 Sep;180(1):209-24.
9
Continuous muscle spasm in intramedullary tumours of the neuraxis.神经轴内髓内肿瘤中的持续性肌肉痉挛。
J Neurol Neurosurg Psychiatry. 1966 Aug;29(4):310-4. doi: 10.1136/jnnp.29.4.310.
10
Subacute "poliomyelitis" and Hodgkin's disease.
J Neurol Sci. 1968 May-Jun;6(3):435-45. doi: 10.1016/0022-510x(68)90029-4.