• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于鉴定编码蓝舌病毒血凝素的基因组片段的基因重配体。

Genetic reassortants for identification of the genome segment coding for the bluetongue virus hemagglutinin.

作者信息

Cowley J A, Gorman B M

出版信息

J Virol. 1987 Jul;61(7):2304-6. doi: 10.1128/JVI.61.7.2304-2306.1987.

DOI:10.1128/JVI.61.7.2304-2306.1987
PMID:3035228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC283696/
Abstract

Two bluetongue virus (BTV) serotypes isolated in Australia and two selected reassortants derived from cells coinfected with these viruses have been used to identify the gene coding for the virus hemagglutinin. The parent viruses had characteristic hemagglutination patterns: BTV type 20 agglutinated sheep erythrocytes only; and BTV type 21 agglutinated sheep, bovine, human, and goose erythrocytes. Analysis of the two virus clones that had reassorted in genes coding for the outer capsid polypeptides demonstrated that hemagglutination and hemagglutination inhibition are functions associated with the outer capsid protein (VP2), which is encoded by genome segment 2.

摘要

在澳大利亚分离出的两种蓝舌病毒(BTV)血清型以及从感染这些病毒的细胞中获得的两种选定重配病毒已被用于鉴定编码病毒血凝素的基因。亲本病毒具有特征性的血凝模式:20型BTV仅凝集绵羊红细胞;21型BTV凝集绵羊、牛、人及鹅的红细胞。对在外衣壳多肽编码基因中发生重配的两个病毒克隆的分析表明,血凝和血凝抑制是与外衣壳蛋白(VP2)相关的功能,VP2由基因组片段2编码。

相似文献

1
Genetic reassortants for identification of the genome segment coding for the bluetongue virus hemagglutinin.用于鉴定编码蓝舌病毒血凝素的基因组片段的基因重配体。
J Virol. 1987 Jul;61(7):2304-6. doi: 10.1128/JVI.61.7.2304-2306.1987.
2
Expression of the outer capsid protein, VP2, from a full length cDNA clone of genome segment 2 of bluetongue serotype 1 from South Africa, using both Sp6 and vaccinia expression systems and a comparison of the nucleic acid sequence of this segment with those of other serotypes.使用Sp6和痘苗表达系统,从南非蓝舌病血清型1基因组第2片段的全长cDNA克隆中表达外衣壳蛋白VP2,并将该片段的核酸序列与其他血清型的序列进行比较。
Virus Res. 1990 Mar;15(3):213-29. doi: 10.1016/0168-1702(90)90029-b.
3
Identification of the gene coding for the hemagglutinin of reovirus.呼肠孤病毒血凝素编码基因的鉴定。
Virology. 1978 May 15;86(2):581-4. doi: 10.1016/0042-6822(78)90099-5.
4
Complete sequence of neutralization protein VP2 of the recent US isolate bluetongue virus serotype 2: its relationship with VP2 species of other US serotypes.近期美国分离的蓝舌病毒血清型2中和蛋白VP2的完整序列:其与美国其他血清型VP2种类的关系
Virus Res. 1988 Aug;11(1):49-58. doi: 10.1016/0168-1702(88)90066-4.
5
Genetic relationships of bluetongue virus serotypes isolated from different parts of the world.从世界不同地区分离出的蓝舌病病毒血清型的遗传关系。
Virus Res. 1988 Aug;11(1):33-47. doi: 10.1016/0168-1702(88)90065-2.
6
Variation in the bluetongue virus neutralization protein VP2.蓝舌病病毒中和蛋白VP2的变异
J Gen Virol. 1987 Nov;68 ( Pt 11):2967-73. doi: 10.1099/0022-1317-68-11-2967.
7
Analysis of mixed infection of sheep with bluetongue virus serotypes 10 and 17: evidence for genetic reassortment in the vertebrate host.绵羊蓝舌病病毒血清型10和17混合感染的分析:脊椎动物宿主中基因重配的证据。
J Virol. 1987 Apr;61(4):1086-91. doi: 10.1128/JVI.61.4.1086-1091.1987.
8
Cross-neutralization of genetic reassortants of bluetongue virus serotypes 20 and 21.蓝舌病病毒血清型20和21基因重配体的交叉中和作用
Vet Microbiol. 1989 Jan;19(1):37-51. doi: 10.1016/0378-1135(89)90089-8.
9
Sequence analysis and in vitro expression of a cDNA clone of genome segment 5 from bluetongue virus, serotype 1 from South Africa.来自南非血清型1蓝舌病毒基因组片段5的cDNA克隆的序列分析及体外表达
Virus Res. 1988 Oct;11(3):227-40. doi: 10.1016/0168-1702(88)90085-8.
10
Identification and characterization of conserved and variable regions in the neutralization VP2 gene of bluetongue virus.蓝舌病病毒中和性VP2基因保守区和可变区的鉴定与特征分析
Virology. 1987 Sep;160(1):100-9. doi: 10.1016/0042-6822(87)90050-x.

引用本文的文献

1
Sialic Acid Binding Sites in VP2 of Bluetongue Virus and Their Use during Virus Entry.唾液酸结合位点在蓝舌病病毒 VP2 中的作用及其在病毒进入过程中的应用。
J Virol. 2022 Jan 12;96(1):e0167721. doi: 10.1128/JVI.01677-21. Epub 2021 Oct 20.
2
An updated review on bluetongue virus: epidemiology, pathobiology, and advances in diagnosis and control with special reference to India.蓝舌病病毒的最新研究进展:流行病学、病理学及诊断与防控技术的改进,特别针对印度。
Vet Q. 2020 Dec;40(1):258-321. doi: 10.1080/01652176.2020.1831708.
3
Development of plant-produced protein body vaccine candidates for bluetongue virus.

本文引用的文献

1
HUMAN BLOOD GROUP INFLUENCE ON REOVIRUS HEMAGGLUTINATION TITERS.人类血型对呼肠孤病毒血凝滴度的影响。
Proc Soc Exp Biol Med. 1964 Apr;115:1118-20. doi: 10.3181/00379727-115-29130.
2
Agglutination of bovine erythrocytes: a general characteristic of reovirus type 3.牛红细胞凝集:呼肠孤病毒3型的一个普遍特征。
Proc Soc Exp Biol Med. 1962 Aug-Sep;110:879-81. doi: 10.3181/00379727-110-27679.
3
Haemagglutination and haemagglutination-inhibition with African horse-sickness virus.非洲马瘟病毒的血细胞凝集及血细胞凝集抑制试验
用于蓝舌病病毒的植物生产蛋白体疫苗候选物的研发。
BMC Biotechnol. 2017 May 30;17(1):47. doi: 10.1186/s12896-017-0370-5.
4
Development and Evaluation of Real Time RT-PCR Assays for Detection and Typing of Bluetongue Virus.用于蓝舌病毒检测与分型的实时逆转录聚合酶链反应检测方法的开发与评估
PLoS One. 2016 Sep 23;11(9):e0163014. doi: 10.1371/journal.pone.0163014. eCollection 2016.
5
Protection of IFNAR (-/-) mice against bluetongue virus serotype 8, by heterologous (DNA/rMVA) and homologous (rMVA/rMVA) vaccination, expressing outer-capsid protein VP2.通过表达外壳蛋白 VP2 的异源(DNA/rMVA)和同源(rMVA/rMVA)疫苗接种,保护 IFNAR(-/-)小鼠免受 8 型蓝舌病毒的侵害。
PLoS One. 2013 Apr 12;8(4):e60574. doi: 10.1371/journal.pone.0060574. Print 2013.
6
Determinants of bluetongue virus virulence in murine models of disease.蓝舌病病毒在疾病小鼠模型中的毒力决定因素。
J Virol. 2011 Nov;85(21):11479-89. doi: 10.1128/JVI.05226-11. Epub 2011 Aug 24.
7
Oncolytic bluetongue viruses: promise, progress, and perspectives.溶瘤性蓝舌病毒:前景、进展与展望
Front Microbiol. 2011 Mar 16;2:46. doi: 10.3389/fmicb.2011.00046. eCollection 2011.
8
Bluetongue virus outer capsid protein VP5 interacts with membrane lipid rafts via a SNARE domain.蓝舌病毒外衣壳蛋白VP5通过SNARE结构域与膜脂筏相互作用。
J Virol. 2008 Nov;82(21):10600-12. doi: 10.1128/JVI.01274-08. Epub 2008 Aug 27.
9
Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress.蓝舌病毒外 capsid 蛋白 VP2 与波形蛋白之间的相互作用是病毒释放所必需的。
Virol J. 2007 Jan 15;4:7. doi: 10.1186/1743-422X-4-7.
10
Expression and functional characterization of bluetongue virus VP2 protein: role in cell entry.蓝舌病病毒VP2蛋白的表达及功能特性:在细胞进入过程中的作用
J Virol. 1999 Dec;73(12):9832-42. doi: 10.1128/JVI.73.12.9832-9842.1999.
Nature. 1961 Jan 21;189:249. doi: 10.1038/189249a0.
4
Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses.节肢动物传播病毒的血凝及血凝抑制技术。
Am J Trop Med Hyg. 1958 Sep;7(5):561-73. doi: 10.4269/ajtmh.1958.7.561.
5
Hemagglutination of epizootic hemorrhagic disease virus.流行性出血病病毒的血细胞凝集
Arch Virol. 1981;69(3-4):291-4. doi: 10.1007/BF01317344.
6
Nucleotide sequences of influenza virus segments 1 and 3 reveal mosaic structure of a small viral RNA segment.流感病毒第1和第3节段的核苷酸序列揭示了一个小病毒RNA节段的镶嵌结构。
Cell. 1982 Feb;28(2):303-13. doi: 10.1016/0092-8674(82)90348-8.
7
Influenza defective interfering viral RNA is formed by internal deletion of genomic RNA.流感缺陷干扰病毒RNA是由基因组RNA内部缺失形成的。
Proc Natl Acad Sci U S A. 1980 Jan;77(1):215-9. doi: 10.1073/pnas.77.1.215.
8
Assignment of the genome segments of bluetongue virus type 1 to the proteins which they encode.蓝舌病病毒1型基因组片段与其所编码蛋白质的对应关系。
Virology. 1984 May;135(1):207-17. doi: 10.1016/0042-6822(84)90131-4.
9
Identification of bluetongue virus type 17 genome segments coding for polypeptides associated with virus neutralization and intergroup reactivity.鉴定编码与病毒中和及组间反应性相关多肽的蓝舌病病毒17型基因组片段。
Virology. 1983 Dec;131(2):355-66. doi: 10.1016/0042-6822(83)90503-2.
10
Molecular basis of bluetongue virus neutralization.蓝舌病病毒中和作用的分子基础。
J Virol. 1983 Dec;48(3):627-32. doi: 10.1128/JVI.48.3.627-632.1983.