Cancer Discov. 2018 Dec;8(12):1498. doi: 10.1158/2159-8290.CD-NB2018-131. Epub 2018 Oct 23.
A recent study suggests that natural killer (NK) cells may play an important role in antitumor response to immune checkpoint inhibitors. Researchers used mouse models to show that NK cells respond to PD-1 and PD-L1 inhibitors, information that could be used to develop immunotherapies that tap NK cells to combat cancer.
最近的一项研究表明,自然杀伤(NK)细胞可能在对免疫检查点抑制剂的抗肿瘤反应中发挥重要作用。研究人员使用小鼠模型表明,NK细胞对PD-1和PD-L1抑制剂有反应,这一信息可用于开发利用NK细胞对抗癌症的免疫疗法。