Laboratory of Modern Acoustics, Department of Physics, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, 210093, China.
Shenzhen Research Institute of Nanjing University, Shenzhen, 51800, China.
Sci Rep. 2018 Oct 23;8(1):15611. doi: 10.1038/s41598-018-34039-w.
In the inhomogeneous medium, acoustic scattering is always a fundamental challenge for photoacoustic imaging. We implement a correlation full-matrix filter (CFMF) combing with a time reversal operator to improve the imaging quality of acoustic sources in complex media. The correlation full-matrix filtering process extracts the direct wave component from the detected signal and preserve all the useful information at the same time. A location factor is considered in the time reversal operator to compensate for the image distortion and false contrast caused by the limited-view detection. The numerical simulations demonstrate that the proposed approach can perform good imaging quality with the higher image signal-noise ratio and better resolution in an acoustic scattering environment. This scheme might be applied to improve the photoacoustic imaging for inhomogeneous biological tissues.
在非均匀介质中,声散射一直是光声成象的一个基本挑战。我们实现了相关全矩阵滤波器(CFMF)与时间反转操作符的结合,以提高复杂介质中声源的成象质量。相关全矩阵滤波过程从检测信号中提取直达波分量,同时保留所有有用信息。在时间反转操作符中考虑了位置因子,以补偿由于有限视场检测而导致的图像失真和假对比度。数值模拟表明,该方法可以在声散射环境中获得更高的图像信噪比和更好的分辨率,从而实现更好的成象质量。该方案可应用于提高非均匀生物组织的光声成象。