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钝性脑血管损伤的处理。

Management of Blunt Cerebrovascular Injury.

机构信息

Department of Neurology, University of Florida, 1149 Newell Dr., PO Box 100236, Gainesville, FL, 32610, USA.

出版信息

Curr Neurol Neurosci Rep. 2018 Oct 23;18(12):98. doi: 10.1007/s11910-018-0906-7.

Abstract

PURPOSE OF REVIEW

This review provides an updated summary of blunt cerebrovascular injury (BCVI) to guide clinicians in its early diagnosis and prevention and treatment of stroke associated with such injury.

RECENT FINDINGS

Untreated BCVI causes stroke in 10-40% of patients, but more than half will not present with stroke symptoms initially. Risk of stroke is highest in the first 7 days, with a peak in the first 24 h. Computed tomography (CT) angiography is currently the screening modality of choice, although digital subtraction angiography may still be required in some cases. Antithrombotic therapy is the mainstay of treatment and has proven safety in trauma patients. In carefully selected patients, endovascular intervention may also be beneficial. BCVI is a potentially preventable cause of stroke. A high index of suspicion is needed as emergent screening during initial evaluation can provide a window for stroke prevention. Screening all patients with injuries that would otherwise prompt CT scans of the neck or chest is recommended. Treatment is guided by grade of injury. Early treatment with antithrombotics has been shown to be both effective and safe.

摘要

目的综述

本文对钝性脑血管损伤(BCVI)进行了更新总结,旨在为临床医生提供早期诊断、预防和治疗与该损伤相关的卒中提供指导。

最新发现

未经治疗的 BCVI 可导致 10-40%的患者发生卒中,但超过一半的患者最初不会出现卒中症状。卒中风险在伤后 7 天内最高,24 小时内达到峰值。目前,计算机断层扫描血管造影(CTA)是首选的筛查手段,尽管在某些情况下仍可能需要数字减影血管造影(DSA)。抗血栓治疗是主要的治疗方法,已被证明在创伤患者中是安全的。在精心选择的患者中,血管内介入治疗也可能有益。BCVI 是一种潜在可预防的卒中病因。在初始评估期间进行紧急筛查可以为预防卒中提供机会,因此需要高度怀疑该病。建议对所有可能导致颈部或胸部 CT 扫描的损伤患者进行筛查。治疗方法取决于损伤的严重程度。早期应用抗血栓药物治疗已被证明既有效又安全。

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