• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Rostral Ventrolateral Medulla and Hypertension.延髓头端腹外侧与高血压
Hypertension. 2018 Sep;72(3):559-566. doi: 10.1161/HYPERTENSIONAHA.118.10921.
2
Decreases in blood pressure and sympathetic nerve activity by microvascular decompression of the rostral ventrolateral medulla in essential hypertension.原发性高血压患者经延髓头端腹外侧微血管减压后血压及交感神经活动降低。
Stroke. 1999 Aug;30(8):1707-10. doi: 10.1161/01.str.30.8.1707.
3
Inhibition of NADPH Oxidase-Dependent Oxidative Stress in the Rostral Ventrolateral Medulla Mediates the Antihypertensive Effects of Acupuncture in Spontaneously Hypertensive Rats.针刺在延髓腹外侧部抑制 NADPH 氧化酶依赖性氧化应激介导自发性高血压大鼠的降压作用。
Hypertension. 2018 Feb;71(2):356-365. doi: 10.1161/HYPERTENSIONAHA.117.09759. Epub 2017 Dec 11.
4
Inhibition of oxidative stress in rostral ventrolateral medulla improves impaired baroreflex sensitivity in stroke-prone spontaneously hypertensive rats.抑制延髓头端腹外侧区的氧化应激可改善易卒中型自发性高血压大鼠受损的压力反射敏感性。
Int Heart J. 2012;53(3):193-8. doi: 10.1536/ihj.53.193.
5
The rostral and caudal ventrolateral medulla in young spontaneously hypertensive rats.
Brain Res. 1990 Jan 1;506(1):153-8. doi: 10.1016/0006-8993(90)91213-z.
6
Exercise Training Attenuates Proinflammatory Cytokines, Oxidative Stress and Modulates Neurotransmitters in the Rostral Ventrolateral Medulla of Salt-Induced Hypertensive Rats.运动训练可减轻盐诱导高血压大鼠延髓头端腹外侧区的促炎细胞因子、氧化应激并调节神经递质。
Cell Physiol Biochem. 2018;48(3):1369-1381. doi: 10.1159/000492095. Epub 2018 Jul 26.
7
Brainstem mechanisms of hypertension: role of the rostral ventrolateral medulla.高血压的脑干机制:延髓头端腹外侧区的作用
Curr Hypertens Rep. 2003 Jun;5(3):262-8. doi: 10.1007/s11906-003-0030-0.
8
Calorie restriction inhibits sympathetic nerve activity via anti-oxidant effect in the rostral ventrolateral medulla of obesity-induced hypertensive rats.热量限制通过抗氧化作用抑制肥胖诱导的高血压大鼠延髓腹外侧头端交感神经活动。
Clin Exp Hypertens. 2011;33(4):240-5. doi: 10.3109/10641963.2011.583969.
9
Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.延髓头端腹外侧区活性氧增加促成易卒中型自发性高血压大鼠高血压的神经机制。
Circulation. 2004 May 18;109(19):2357-62. doi: 10.1161/01.CIR.0000128695.49900.12. Epub 2004 Apr 26.
10
Pulsatile compression of the rostral ventrolateral medulla in hypertension.高血压时延髓头端腹外侧区的搏动性压迫
Hypertension. 1997 Jan;29(1 Pt 2):514-8. doi: 10.1161/01.hyp.29.1.514.

引用本文的文献

1
The Heart-Brain Axis in the Artificial Intelligence Era: Integrating Old and New Insights Towards New Targeting and Innovative Neuro- and Cardio-Therapeutics.人工智能时代的脑心轴:整合新旧见解以实现新的靶向及创新神经和心脏治疗
Int J Mol Sci. 2025 Aug 24;26(17):8217. doi: 10.3390/ijms26178217.
2
Klotho microinjection into the RVLM attenuates acute kidney injury interaction with the cholinergic anti-inflammatory pathway in rats.向大鼠延髓头端腹外侧区微量注射α-klotho可减轻急性肾损伤,并与胆碱能抗炎通路相互作用。
Res Pharm Sci. 2025 Jun 17;20(3):343-355. doi: 10.4103/RPS.RPS_46_24. eCollection 2025 Jun.
3
Dynamic rewiring of microRNA networks in the brainstem autonomic control circuits during hypertension development in the female spontaneously hypertensive rat.雌性自发性高血压大鼠高血压发展过程中脑干自主神经控制回路中微小RNA网络的动态重塑
Physiol Genomics. 2025 Jul 18. doi: 10.1152/physiolgenomics.00136.2024.
4
Adult-onset Leigh syndrome with recurrent seizures and peripheral neuropathy due to the 9176T > C mutation: a case report and literature review.成人起病的 Leigh 综合征伴 9176T > C 突变所致反复癫痫发作和周围神经病变:一例报告及文献复习
BMC Neurol. 2025 Mar 26;25(1):128. doi: 10.1186/s12883-025-04135-2.
5
Resveratrol reduces RVLM neuron activity via activating the AMPK/Sirt3 pathway in stress-induced hypertension.白藜芦醇通过激活应激性高血压中AMPK/Sirt3信号通路降低延髓头端腹外侧区(RVLM)神经元活性。
J Biol Chem. 2025 Apr;301(4):108394. doi: 10.1016/j.jbc.2025.108394. Epub 2025 Mar 10.
6
Janus Kinase 2/Signal Transducer and Activator of Transcription 3/Cyclooxygenase 2 Signaling Pathway Mediates the Effect of Central Angiotensin II on the Elevation of Rostral Ventrolateral Medulla Prostaglandin E-Induced Oxidative Stress in Hypertension.Janus激酶2/信号转导子与转录激活子3/环氧化酶2信号通路介导中枢血管紧张素II对高血压时延髓头端腹外侧前列腺素E诱导的氧化应激升高的影响。
J Am Heart Assoc. 2025 Jan 21;14(2):e036762. doi: 10.1161/JAHA.124.036762. Epub 2025 Jan 16.
7
Angiotensin-(1-7) and Central Control of Cardiometabolic Outcomes: Implications for Obesity Hypertension.血管紧张素 -(1 - 7)与心脏代谢结局的中枢控制:对肥胖高血压的影响
Int J Mol Sci. 2024 Dec 12;25(24):13320. doi: 10.3390/ijms252413320.
8
Large-scale brainstem neuroimaging and genetic analyses provide new insights into the neuronal mechanisms of hypertension.大规模脑干神经影像学和基因分析为高血压的神经元机制提供了新见解。
HGG Adv. 2025 Jan 9;6(1):100392. doi: 10.1016/j.xhgg.2024.100392. Epub 2024 Dec 10.
9
Palmitoylation regulates norepinephrine transporter uptake, surface localization, and total expression with pathogenic implications in postural orthostatic tachycardia syndrome.棕榈酰化调节去甲肾上腺素转运体的摄取、表面定位和总表达,对体位性直立性心动过速综合征具有致病影响。
J Neurochem. 2025 Feb;169(2):e16241. doi: 10.1111/jnc.16241. Epub 2024 Oct 12.
10
A neural perspective on the treatment of hypertension: the neurological network excitation and inhibition (E/I) imbalance in hypertension.高血压治疗的神经学视角:高血压中的神经网络兴奋与抑制(E/I)失衡
Front Cardiovasc Med. 2024 Sep 11;11:1436059. doi: 10.3389/fcvm.2024.1436059. eCollection 2024.

本文引用的文献

1
Inflammatory pathways are central to posterior cerebrovascular artery remodelling prior to the onset of congenital hypertension.炎症通路在先天性高血压发病前的后循环动脉重塑中起核心作用。
J Cereb Blood Flow Metab. 2019 Sep;39(9):1803-1817. doi: 10.1177/0271678X18769180. Epub 2018 Apr 13.
2
Integrative Physiological Aspects of Brain RAS in Hypertension.脑 RAS 在高血压中的整合生理学方面。
Curr Hypertens Rep. 2018 Feb 26;20(2):10. doi: 10.1007/s11906-018-0810-1.
3
Intracranial Pressure Is a Determinant of Sympathetic Activity.颅内压是交感神经活动的一个决定因素。
Front Physiol. 2018 Feb 8;9:11. doi: 10.3389/fphys.2018.00011. eCollection 2018.
4
Variable role of carotid bodies in cardiovascular responses to exercise, hypoxia and hypercapnia in spontaneously hypertensive rats.颈动脉体在自发性高血压大鼠运动、低氧和高碳酸血症心血管反应中的可变作用。
J Physiol. 2018 Aug;596(15):3201-3216. doi: 10.1113/JP275487. Epub 2018 Feb 12.
5
Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptin.瘦素调节区域性自主神经活动中 POMC 和 AgRP 神经元的差异贡献。
Mol Metab. 2018 Feb;8:1-12. doi: 10.1016/j.molmet.2017.12.006. Epub 2017 Dec 18.
6
Interdependent feedback regulation of breathing by the carotid bodies and the retrotrapezoid nucleus.颈动脉体和延髓网状结构对呼吸的相互依存的反馈调节。
J Physiol. 2018 Aug;596(15):3029-3042. doi: 10.1113/JP274357. Epub 2017 Dec 27.
7
DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity.化学感受反射的中枢和传出支中的 DNA 甲基化需要颈动脉体神经活动。
J Physiol. 2018 Aug;596(15):3087-3100. doi: 10.1113/JP274833. Epub 2018 Jan 4.
8
Chronic Intermittent Hypoxia Differentially Impacts Different States of Inspiratory Activity at the Level of the preBötzinger Complex.慢性间歇性低氧对前包钦格复合体水平的不同吸气活动状态有不同影响。
Front Physiol. 2017 Aug 28;8:571. doi: 10.3389/fphys.2017.00571. eCollection 2017.
9
Epigenetic changes by DNA methylation in chronic and intermittent hypoxia.慢性和间歇性缺氧中DNA甲基化引起的表观遗传变化。
Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1096-L1100. doi: 10.1152/ajplung.00325.2017. Epub 2017 Aug 24.
10
The Orexin System and Hypertension.食欲素系统与高血压。
Cell Mol Neurobiol. 2018 Mar;38(2):385-391. doi: 10.1007/s10571-017-0487-z. Epub 2017 Mar 27.

Rostral Ventrolateral Medulla and Hypertension.

作者信息

Guyenet Patrice G, Stornetta Ruth L, Holloway Benjamin B, Souza George M P R, Abbott Stephen B G

机构信息

From the Department of Pharmacology, University of Virginia, Charlottesville.

出版信息

Hypertension. 2018 Sep;72(3):559-566. doi: 10.1161/HYPERTENSIONAHA.118.10921.

DOI:10.1161/HYPERTENSIONAHA.118.10921
PMID:30354763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6324579/
Abstract
摘要