Inria Sophia Antipolis Méditerranée Research Centre, MathNeuro Team, 2004 route des Lucioles-Boíte Postale 93, 06902, Sophia Antipolis, Cedex, France.
Institut für Theoretische Physik, Technische Universität Berlin, Hardenbergstr. 36, 10623, Berlin, Germany.
Sci Rep. 2018 Oct 24;8(1):15748. doi: 10.1038/s41598-018-33990-y.
We investigate the dynamics of a population of identical biomolecules mimicked as electric dipoles with random orientations and positions in space and oscillating with their intrinsic frequencies. The biomolecules, beyond being coupled among themselves via the dipolar interaction, are also driven by a common external energy supply. A collective mode emerges by decreasing the average distance among the molecules as testified by the emergence of a clear peak in the power spectrum of the total dipole moment. This is due to a coherent vibration of the most part of the molecules at a frequency definitely larger than their own frequencies corresponding to a partial cluster synchronization of the biomolecules. These results can be verified experimentally via spectroscopic investigations of the strength of the intermolecular electrodynamic interactions, thus being able to test the possible biological relevance of the observed macroscopic mode.
我们研究了一群通过偶极子相互作用耦合在一起的相同生物分子的动力学，这些偶极子在空间中具有随机取向和位置，并且以其固有频率振荡。生物分子除了通过偶极相互作用相互耦合外，还受到共同外部能源供应的驱动。随着分子间平均距离的减小，出现了一个集体模式，这可以通过总偶极矩的功率谱中出现明显的峰值来证明。这是由于大部分分子以明显大于其自身频率的频率进行相干振动，对应于生物分子的部分簇同步。这些结果可以通过分子间电磁相互作用强度的光谱研究来实验验证，从而能够测试所观察到的宏观模式的可能生物学相关性。
