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组织启发型再生医学界面涂层。

Tissue-Inspired Interfacial Coatings for Regenerative Medicine.

机构信息

Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, South Korea.

Division of Bio-Medical Science and Technology, University of Science and Technology, Daejeon, South Korea.

出版信息

Adv Exp Med Biol. 2018;1077:415-420. doi: 10.1007/978-981-13-0947-2_22.

Abstract

Biomedical devices have come a long way since they were first introduced as a medically interventional methodology in treating various types of diseases. Different techniques were employed to make the devices more biocompatible and promote tissue repair; such as chemical surface modifications, using novel materials as the bulk of a device, physical topological manipulations and so forth. One of the strategies that recently gained a lot of attention is the use of tissue-inspired biomaterials that are coated on the surface of biomedical devices via different coating techniques, such as the use of extracellular matrix (ECM) coatings, extracted cell membrane coatings, and so on. In this chapter, we will give a general overview of the different types of tissue-inspired coatings along with a summary of recent studies reported in this scientific arena.

摘要

自最初作为一种医学介入方法引入治疗各种类型疾病以来,生物医学设备已经取得了长足的进步。为了使设备更具生物相容性和促进组织修复,采用了不同的技术;例如化学表面改性、使用新型材料作为设备的主体、物理拓扑操作等。最近引起广泛关注的策略之一是使用受组织启发的生物材料,通过不同的涂层技术将其涂覆在生物医学设备的表面,例如使用细胞外基质 (ECM) 涂层、提取的细胞膜涂层等。在本章中,我们将概述不同类型的受组织启发的涂层,并总结该科学领域最近的研究报告。

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