应用 R 进行人类遗传学的统计学

Applied Statistics for Human Genetics Using R.

机构信息

Epidemiology and Biostatistics, Loma Linda University School of Medicine and Public Health, Sunnyvale, CA, USA.

出版信息

Adv Exp Med Biol. 2018;1082:123-144. doi: 10.1007/978-3-319-93791-5_3.

Abstract

This chapter considers the fundamental concepts in the theory of probability and applied statistics in epidemiology, including the biostatistical concepts and measures in genetic association and familial aggregation studies, including: Additional Approaches in Familial Aggregation Studies Twin Studies Adoption Studies Inbreeding Studies Randomization Test Segregation studies, Linkage studies, Association studies Genome-wide Association Studies (GWAS) Big Data and Human Genomics.

摘要

本章考虑了概率论和流行病学应用统计学中的基本概念，包括遗传关联和家族聚集研究中的生物统计学概念和度量，包括：家族聚集研究的其他方法双胞胎研究收养研究近交研究随机化检验分离研究、连锁研究、关联研究全基因组关联研究（GWAS）大数据和人类基因组学。