Suppr超能文献

植物基因组中的顺式调控变异和自然选择的影响。

Cis-regulatory variation in plant genomes and the impact of natural selection.

机构信息

Institute of Botany, University of Cologne, Zülpicherstr 47b, 50674, Cologne, Germany.

出版信息

Am J Bot. 2018 Nov;105(11):1788-1791. doi: 10.1002/ajb2.1180. Epub 2018 Oct 25.

Abstract

Understanding the molecular mechanisms that allow phenotypic diversification in response to natural or artificial selection is one of the major challenges of modern biology (Barrett and Hoekstra, 2011). The evolution of gene regulation is a prominent pillar for adaptation in sessile organisms like plants because the activity of genes must be tuned to the environment. Today, we can accurately document the genome-wide distribution of -regulatory variants. Here, I summarize how current data show that both positive selection and purifying selection contribute to shape -regulatory variation. To disentangle their relative impact, I argue that -regulatory and amino-acid evolutionary rates should be analyzed jointly.

摘要

理解分子机制,使表型多样化以适应自然或人为选择,是现代生物学的主要挑战之一(Barrett 和 Hoekstra,2011)。基因调控的进化是植物等固着生物适应的重要支柱,因为基因的活性必须适应环境。如今,我们可以准确地记录基因组范围内 -调控变体的分布。在这里,我总结了当前的数据如何表明,正选择和净化选择都有助于塑造 -调控变异。为了理清它们的相对影响,我认为应该联合分析 -调控和氨基酸进化速率。

相似文献

1
Cis-regulatory variation in plant genomes and the impact of natural selection.
Am J Bot. 2018 Nov;105(11):1788-1791. doi: 10.1002/ajb2.1180. Epub 2018 Oct 25.
2
Genomic analysis reveals major determinants of cis-regulatory variation in Capsella grandiflora.
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1087-1092. doi: 10.1073/pnas.1612561114. Epub 2017 Jan 17.
3
The effect of transposable elements on phenotypic variation: insights from plants to humans.
Sci China Life Sci. 2016 Jan;59(1):24-37. doi: 10.1007/s11427-015-4993-2. Epub 2016 Jan 11.
5
Variation in susceptibility to Wheat dwarf virus among wild and domesticated wheat.
PLoS One. 2015 Apr 2;10(4):e0121580. doi: 10.1371/journal.pone.0121580. eCollection 2015.
6
The impact of linked selection on plant genomic variation.
Brief Funct Genomics. 2014 Jul;13(4):268-75. doi: 10.1093/bfgp/elu009. Epub 2014 Apr 23.
7
Plant genomes do a balancing act.
Mol Ecol. 2009 Jul;18(13):2743-5. doi: 10.1111/j.1365-294X.2009.04205.x. Epub 2009 Apr 24.
8
Selection on major components of angiosperm genomes.
Science. 2008 Apr 25;320(5875):484-6. doi: 10.1126/science.1153586.
10
Association mapping reveals the role of purifying selection in the maintenance of genomic variation in gene expression.
Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15390-5. doi: 10.1073/pnas.1503027112. Epub 2015 Nov 24.

引用本文的文献

1
Enhancers in Plant Development, Adaptation and Evolution.
Plant Cell Physiol. 2025 May 17;66(4):461-476. doi: 10.1093/pcp/pcae121.
2
Predicting gene expression responses to environment in using natural variation in DNA sequence.
bioRxiv. 2025 Mar 4:2024.04.25.591174. doi: 10.1101/2024.04.25.591174.
5
Parental legacy and regulatory novelty in diurnal transcriptomes accompanying their polyploidy.
NAR Genom Bioinform. 2020 Sep 22;2(3):lqaa067. doi: 10.1093/nargab/lqaa067. eCollection 2020 Sep.
7
Genetic and molecular basis of floral induction in Arabidopsis thaliana.
J Exp Bot. 2020 May 9;71(9):2490-2504. doi: 10.1093/jxb/eraa057.
8
Towards the new normal: Transcriptomic convergence and genomic legacy of the two subgenomes of an allopolyploid weed (Capsella bursa-pastoris).
PLoS Genet. 2019 May 13;15(5):e1008131. doi: 10.1371/journal.pgen.1008131. eCollection 2019 May.

本文引用的文献

1
The Evolution of Gene Expression in cis and trans.
Trends Genet. 2018 Jul;34(7):532-544. doi: 10.1016/j.tig.2018.03.007. Epub 2018 Apr 18.
4
Genomic analysis reveals major determinants of cis-regulatory variation in Capsella grandiflora.
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1087-1092. doi: 10.1073/pnas.1612561114. Epub 2017 Jan 17.
5
The Footprint of Polygenic Adaptation on Stress-Responsive Cis-Regulatory Divergence in the Arabidopsis Genus.
Mol Biol Evol. 2016 Aug;33(8):2088-101. doi: 10.1093/molbev/msw096. Epub 2016 May 11.
6
Recent mating-system evolution in Eichhornia is accompanied by cis-regulatory divergence.
New Phytol. 2016 Jul;211(2):697-707. doi: 10.1111/nph.13918. Epub 2016 Mar 15.
7
Local Adaptation by Alleles of Small Effect.
Am Nat. 2015 Oct;186 Suppl 1:S74-89. doi: 10.1086/682405. Epub 2015 Aug 25.
8
Enhancer Runaway and the Evolution of Diploid Gene Expression.
PLoS Genet. 2015 Nov 12;11(11):e1005665. doi: 10.1371/journal.pgen.1005665. eCollection 2015 Nov.
9
Cis-Regulatory Changes Associated with a Recent Mating System Shift and Floral Adaptation in Capsella.
Mol Biol Evol. 2015 Oct;32(10):2501-14. doi: 10.1093/molbev/msv169. Epub 2015 Aug 28.
10
The role of cis regulatory evolution in maize domestication.
PLoS Genet. 2014 Nov 6;10(11):e1004745. doi: 10.1371/journal.pgen.1004745. eCollection 2014 Nov.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验