Suppr超能文献

30只犬接受微脉冲经巩膜睫状体光凝术治疗难治性青光眼的初步研究结果。

Preliminary findings in 30 dogs treated with micropulse transscleral cyclophotocoagulation for refractory glaucoma.

作者信息

Sapienza John S, Kim Kay, Rodriguez Elena, DiGirolamo Nicola

机构信息

Long Island Veterinary Specialists, Plainview, New York.

Tai Wai Small Animal Clinic & Exotic Hospital, Hong Kong, China.

出版信息

Vet Ophthalmol. 2019 Jul;22(4):520-528. doi: 10.1111/vop.12622. Epub 2018 Oct 25.

Abstract

OBJECTIVE

The purpose of this study was to report the preliminary results of a novel micropulse transscleral diode laser cyclophotocoagulation (MP-TSCP) as primary therapy for glaucomatous dogs.

ANIMAL STUDIED

Client owned dogs undergoing MP-TSCP therapy at a veterinary referral center.

PROCEDURE

Retrospective study of dogs with glaucoma that were treated with MP-TSCP with a minimum of 1 month (range: 1-18 months) of follow-up. Reported outcomes were intraocular pressure (IOP), treatment parameters, reduction in medications, complications, and incidence of repeat therapy.

RESULTS

Thirty dogs (35 eyes) were evaluated. The mean age was 9.0 years. Mean preoperative IOP was 34.5 mm Hg. Mean postoperative IOP at 1 month (35/35 eyes) was 22 mm Hg, 2 months (26/35 eyes) was 20.5 mm Hg, 4 months (20/35 eyes) was 19 mm Hg, 6 months (10/35 eyes) was 19 mm Hg, 12 months (8/35 eyes) was 21 mm Hg. First treatment success rate was 19/35 eyes (54.3%). Repeat laser was performed in 11 eyes with 4/11 eyes responding favorably for a total IOP control of 23/35 eyes (65.7%). Mean energy levels employed were 137.5 seconds and 2351 mW at 31.3% duty cycle. Reduction in medications was from a mean of 3.6 medications preoperatively to 3.1 medications postoperatively. Complications included corneal ulcers 5/35 eyes (14.3%), uncontrolled IOP in 12/35 eyes (34.3%) and repeat treatment in 11/35 eyes (31.4%).

CONCLUSIONS

MP-TSCP was successful in controlling IOP in most patients as well as to reduce postoperative medications with minimal resultant intraocular inflammation and complications. The micropulse procedure also can be repeated. Future investigations to study effective treatment parameters are warranted in a larger series of patients over a longer period of evaluation.

摘要

目的

本研究旨在报告一种新型微脉冲经巩膜二极管激光睫状体光凝术(MP - TSCP)作为青光眼犬原发性治疗方法的初步结果。

研究动物

在一家兽医转诊中心接受MP - TSCP治疗的客户拥有的犬只。

过程

对接受MP - TSCP治疗且随访时间至少1个月(范围:1 - 18个月)的青光眼犬进行回顾性研究。报告的结果包括眼压(IOP)、治疗参数、药物用量减少情况、并发症以及重复治疗的发生率。

结果

评估了30只犬(35只眼)。平均年龄为9.0岁。术前平均眼压为34.5毫米汞柱。术后1个月(35/35只眼)平均眼压为22毫米汞柱,2个月(26/35只眼)为20.5毫米汞柱,4个月(20/35只眼)为19毫米汞柱,6个月(10/35只眼)为19毫米汞柱,12个月(8/35只眼)为21毫米汞柱。首次治疗成功率为19/35只眼(54.3%)。对11只眼进行了重复激光治疗,其中4/11只眼反应良好,眼压总体控制率为23/35只眼(65.7%)。平均使用的能量水平为137.5秒,占空比31.3%时功率为2351毫瓦。药物用量从术前平均3.6种减少到术后3.1种。并发症包括角膜溃疡5/35只眼(14.3%)、眼压控制不佳12/35只眼(34.3%)以及重复治疗11/35只眼(31.4%)。

结论

MP - TSCP在大多数患者中成功控制了眼压,并减少了术后药物用量,同时眼内炎症和并发症最少。微脉冲手术也可重复进行。未来有必要在更大规模的患者群体中进行更长时间的评估,以研究有效的治疗参数。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验