Motoi I, Nakajima K, Nitta M, Yamaguchi K, Kumaki O, Tokunaga S, Shimamura M, Hisazumi H, Nonomura A
Hinyokika Kiyo. 1987 Feb;33(2):259-63.
A case of Wilms' tumor in an adult patient is presented. The tumor in adults is rather rare and has an unfavorable prognosis. A 39-year-old man bruised his left flank while skiing in February, 1983. He noticed severe left flank pain. The pain subsided after a week of rest. However, he complained of left abdominal mass and dull pain again, and consulted our outpatient clinic on May 21, 1983. Left transperitoneal nephrectomy was performed under a diagnosis of left injured renal tumor. Histological diagnosis was nephroblastoma. A combined chemotherapy of actinomycin D (ACD) and vincristine (VCR) was started after operation. A total of 10 mg of ACD and 14 mg of VCR was administered by the end of 1983. In March 1984, however, a local recurrence and pulmonary metastases of the tumor were detected by CT and chest films. Local RF-hyperthermia combined with irradiation, alpha-interferon or chemotherapy using cisplatin and adriamycin was given. The patient died of profound cachexia in December, 1984 after gradual deterioration of general conditions.
本文报告一例成年患者的肾母细胞瘤。成人肾母细胞瘤较为罕见，预后不佳。一名39岁男性于1983年2月滑雪时左侧胁腹受伤。他感到左侧胁腹剧痛。休息一周后疼痛缓解。然而，他再次出现左腹部肿块和隐痛，并于1983年5月21日到我院门诊就诊。诊断为左肾肿瘤损伤后，实施了左经腹肾切除术。组织学诊断为肾母细胞瘤。术后开始联合应用放线菌素D（ACD）和长春新碱（VCR）进行化疗。到1983年底，共给予10毫克ACD和14毫克VCR。然而，1984年3月，通过CT和胸部X线片发现肿瘤局部复发并伴有肺转移。给予局部射频热疗联合放疗、α干扰素或使用顺铂和阿霉素的化疗。患者在全身状况逐渐恶化后，于1984年12月死于严重恶病质。
