Department of Trauma and Orthopaedics, Bezmialem Vakif University, Adnan Menderes Bulvarı, Vatan Caddesi, Istanbul, Turkey.
Department of Trauma and Orthopaedics, The Royal London Hospital, Whitechapel, London, E1 1BB, United Kingdom.
Surgeon. 2019 Oct;17(5):291-299. doi: 10.1016/j.surge.2018.09.001. Epub 2018 Oct 22.
Proponents of the direct anterior approach (DAA) for THAs suggest earlier recovery with no increased complications whereas opponents suggest higher complication rates.
We conducted a meta-analysis of randomized controlled trials (RCTs) to compare the outcomes of the DAA versus other surgical approaches in primary THAs.
We identified 18 RCTs suitable for detailed extraction of the data. The RCTs included a total of 1661 patients with a mean age of 62 years (range 55-69). Using the DAA led to a significant improvement in the Harris Hip score by a mean of 5.6 points (95% confidence interval (CI) 4.3 to 6.8, p < 0.01, heterogeneity I 18%) and the WOMAC score by a mean of -3.1 points (95% CI -4.1 to -2.1, p < 0.001, I 0%) at 6 weeks postoperatively, reduction in the analgesic requirements on the day of surgery (Morphine Equivalents -3.6 95% CI -6.5 to -0.7, p = 0.02, I 50%) and pain scores on day one postoperatively (VAS -1.3 95% CI -1.5 to -1.1, p < 0.01, I 91%). DAA was associated with a smaller incision (-3.2 cm 95% CI -3.3 to -3.1, p < 0.01, I 99%) and there was no significant difference in complication rates (P = 0.20) among the study groups.
Based on the available studies, the DAA offers superior functional outcomes over other approaches in the immediate postoperative period after primary THA with no increased risk of complications. However, there was no evidence to support the superiority of any approach beyond 6 weeks postoperatively.
直接前入路(DAA)髋关节置换术的支持者认为,该手术恢复更快,且不会增加并发症,而反对者则认为该手术的并发症发生率更高。
我们对随机对照试验(RCT)进行了荟萃分析,以比较 DAA 与其他手术入路在初次全髋关节置换术中的结果。
我们确定了 18 项适合详细提取数据的 RCT。这些 RCT 共纳入了 1661 名平均年龄为 62 岁(55-69 岁)的患者。与其他手术入路相比,使用 DAA 可使术后 6 周的 Harris 髋关节评分平均提高 5.6 分(95%置信区间(CI)为 4.3-6.8,p<0.01,异质性 I 为 18%),WOMAC 评分平均降低-3.1 分(95%CI-4.1 至-2.1,p<0.001,I 为 0%),术后当天的镇痛需求减少(吗啡等效物-3.6,95%CI-6.5 至-0.7,p=0.02,I 为 50%),术后第一天的疼痛评分降低(VAS-1.3,95%CI-1.5 至-1.1,p<0.01,I 为 91%)。DAA 与更小的切口相关(-3.2cm,95%CI-3.3 至-3.1,p<0.01,I 为 99%),且各研究组之间的并发症发生率无显著差异(P=0.20)。
基于现有研究,与其他手术入路相比,DAA 在初次全髋关节置换术后的即刻阶段提供了更好的功能结果,且不会增加并发症风险。然而,在术后 6 周后,没有证据支持任何一种手术入路具有优越性。