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人类红细胞中嘌呤核苷酸的再利用途径。

Reutilization pathway of purine nucleotides in human erythrocytes.

作者信息

Salerno C, Giacomello A, Crifo C, Capuozzo E

出版信息

Biomed Biochim Acta. 1987;46(2-3):S273-7.

PMID:3036113
Abstract

Human erythrocytes can operate the pyrophosphorolysis of IMP and utilize the phosphoribosyl moiety of this compound for the synthesis of AMP and of GMP from exogenous purine bases. Erythrocyte purine phosphoribosyltransferases seem to have a role in this interconversion pathway.

摘要

人类红细胞能够进行肌苷一磷酸(IMP)的焦磷酸解,并利用该化合物的磷酸核糖部分,从外源性嘌呤碱基合成一磷酸腺苷(AMP)和鸟苷一磷酸(GMP)。红细胞嘌呤磷酸核糖转移酶似乎在这一相互转化途径中发挥作用。

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