Adam S
Int J Radiat Biol Relat Stud Phys Chem Med. 1977 Sep;32(3):219-27. doi: 10.1080/09553007714550931.
gamma-radiolysis of aqueous N2O-saturated solutions of alpha, alpha-trehalose (10(-2) M) with doses of 500 krad yielded glucose (G = 2.3), gluconic acid lactone (G = 0.25) and--after reduction--iditol (G = 0.15), mannitol (G = 0.05), 5-deoxy-glucitol (G = 0.34) and 2-deoxy-glucitol (G = 0.14). The decomposition of trehalose (G = -5.9) was reduced, if equimolar amounts of amino acids (alanine, leucine, phenylalanine, methionine or cysteine) were present during irradiation. The extent of this reduction has been correlated with the .OH radical-scavenging properties of the added amino acids. Cysteine also protected trehalose by the repair of initially formed trehalose radicals and almost completely suppressed the formation of products. The addition of the remaining amino acids led to an increase of molar product yields (glucose, 5-deoxy-glucitol and 2-deoxy-glucitol), which was related to the decomposition of trehalose. This finding was explained by hydrogen transfer from the amino acids to precursor radicals of the products.
用500千拉德的剂量对α,α-海藻糖（10⁻² M）的N₂O饱和水溶液进行γ辐解，产生了葡萄糖（G = 2.3）、葡萄糖酸内酯（G = 0.25）以及还原后的艾杜醇（G = 0.15）、甘露醇（G = 0.05）、5-脱氧葡糖醇（G = 0.34）和2-脱氧葡糖醇（G = 0.14）。如果在辐照过程中存在等摩尔量的氨基酸（丙氨酸、亮氨酸、苯丙氨酸、蛋氨酸或半胱氨酸），海藻糖的分解（G = -5.9）会减少。这种减少的程度与所添加氨基酸的·OH自由基清除特性相关。半胱氨酸还通过修复最初形成的海藻糖自由基来保护海藻糖，并几乎完全抑制了产物的形成。添加其余氨基酸会导致摩尔产物产率（葡萄糖、5-脱氧葡糖醇和2-脱氧葡糖醇）增加，这与海藻糖的分解有关。这一发现可通过氨基酸向产物的前体自由基进行氢转移来解释。
