Wardas J, Ossowska K, Wolfarth S
Brain Res. 1987 Apr 7;408(1-2):363-6. doi: 10.1016/0006-8993(87)90406-9.
Picrotoxin or bicuculline were injected bilaterally into the zona incerta-lateral hypothalamus (ZI-LH) of the rat. Each drug (50 ng) inhibited or abolished the catalepsy induced by 20 mg/kg s.c. of morphine. Each drug also strongly inhibited the tonic electromyographic activity (EMG) induced by 10 mg/kg s.c. of morphine in the gastrocnemius soleus muscle (GS). The obtained results demonstrate participation of the ZI-LH in both catalepsy and rigidity induced by a systemic administration of morphine.
将印防己毒素或荷包牡丹碱双侧注射到大鼠的未定带-外侧下丘脑（ZI-LH）。每种药物（50纳克）均抑制或消除了皮下注射20毫克/千克吗啡所诱发的僵住症。每种药物还强烈抑制了皮下注射10毫克/千克吗啡在腓肠肌比目鱼肌（GS）中诱发的强直肌电图活动（EMG）。所得结果表明ZI-LH参与了全身给予吗啡所诱发的僵住症和强直。
