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来自水稻防御素OsAFP1的部分肽对稻瘟病菌表现出抗真菌活性。

Partial peptides from rice defensin OsAFP1 exhibited antifungal activity against the rice blast pathogen .

作者信息

Sagehashi Yoshiyuki, Takaku Hiroaki, Yatou Osamu

机构信息

Hokkaido Agricultural Research Center, National Agriculture and Food Research Organization.

Department of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences.

出版信息

J Pestic Sci. 2017 Nov 24;42(4):172-175. doi: 10.1584/jpestics.D17-046.

DOI:10.1584/jpestics.D17-046
PMID:30363094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6140636/
Abstract

Rice blast caused by is one of the most devastating diseases worldwide. This study aimed to investigate the antifungal activity of rice defensin OsAFP1 and its partial peptides against . The partial peptides near the N- and C-terminal regions of OsAFP1 exhibited approximately the same antifungal activity as the entire protein against . These partial peptides have the potential to be used as fungicides.

摘要

由[未提及病原菌名称]引起的稻瘟病是全球最具毁灭性的病害之一。本研究旨在探究水稻防御素OsAFP1及其部分肽段对[未提及病原菌名称]的抗真菌活性。OsAFP1 N端和C端区域附近的部分肽段对[未提及病原菌名称]表现出与完整蛋白大致相同的抗真菌活性。这些部分肽段有潜力用作杀菌剂。

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本文引用的文献

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Two novel antimicrobial defensins from rice identified by gene coexpression network analyses.通过基因共表达网络分析鉴定出的两种来自水稻的新型抗菌防御素。
Peptides. 2016 Oct;84:7-16. doi: 10.1016/j.peptides.2016.07.005. Epub 2016 Aug 12.
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Antifungal plant defensins: mechanisms of action and production.抗真菌植物防御素:作用机制与产生
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Phosphoinositide-mediated oligomerization of a defensin induces cell lysis.磷酸肌醇介导的防御素寡聚化诱导细胞裂解。
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Antifungal activity of plant defensin AFP1 in Brassica juncea involves the recognition of the methyl residue in glucosylceramide of target pathogen Candida albicans.芥菜中植物防御素AFP1的抗真菌活性涉及对靶标病原体白色念珠菌糖基神经酰胺中甲基残基的识别。
Curr Genet. 2014 May;60(2):89-97. doi: 10.1007/s00294-013-0416-8. Epub 2013 Nov 20.
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A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori.一种来自番茄防御素的新型合成肽对幽门螺杆菌具有抗菌活性。
J Pept Sci. 2012 Dec;18(12):755-62. doi: 10.1002/psc.2462. Epub 2012 Nov 4.
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Emerging fungal threats to animal, plant and ecosystem health.新兴真菌对动物、植物和生态系统健康的威胁。
Nature. 2012 Apr 11;484(7393):186-94. doi: 10.1038/nature10947.
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Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation.宿主防御肽的抗生素活性:远不止于脂质双层扰动。
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