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Cerebellar Na+,K+-ATPase activity is increased during early postnatal development of the estrogenized female rat.

作者信息

Litteria M

出版信息

Brain Res. 1987 May;430(1):157-60. doi: 10.1016/0165-3806(87)90188-x.

DOI:10.1016/0165-3806(87)90188-x
PMID:3036319
Abstract

The activities of Na+,K+-ATPase and Mg2+-ATPase were measured in the crude P2 synaptosomal fraction of the cerebellum through age 35 days in female rats injected s.c. with 500 micrograms estradiol benzoate 24 h after birth. Estrogenization did not affect Mg2+-ATPase. However, the activity of Na+,K+-ATPase was significantly increased above control values between ages 5 and 20 days. These data demonstrate an age-dependent estrogen-induced effect on cerebellar Na+,K+-ATPase during early postnatal development.

摘要

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