多巴胺激动剂和拮抗剂对突触体钠钾ATP酶和镁ATP酶活性的影响。
The effects of dopamine agonists and antagonists on Na+,K+-ATPase and Mg2+-ATPase activities of synaptosomes.
作者信息
Sawas A H, Gilbert J C
出版信息
Biochem Pharmacol. 1982 Apr 15;31(8):1531-3. doi: 10.1016/0006-2952(82)90377-x.
PMID:6124258
Abstract
The effects of dopamine agonists and antagonists on the Na+,K+-ATPase and Mg2+-ATPase activities of rat cerebral cortex synaptosomes have been determined. Dopamine, ADTN, apomorphine and S-584, but not piribedil, stimulated the activities of the enzymes. The stimulatory effect of dopamine was not antagonised by dopamine antagonists and apparently the catechol group is responsible for the enzyme stimulation.
摘要
已测定多巴胺激动剂和拮抗剂对大鼠大脑皮层突触体的Na +，K + -ATP酶和Mg2 + -ATP酶活性的影响。多巴胺、ADTN、阿扑吗啡和S-584可刺激这些酶的活性，但匹莫齐尔则无此作用。多巴胺拮抗剂不能拮抗多巴胺的刺激作用，显然儿茶酚基团是酶刺激作用的原因。
Zotero 插件