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帕金森病中集合不足的患病率

Prevalence of Convergence Insufficiency in Parkinson's Disease.

作者信息

Irving Elizabeth L, Chriqui Estefania, Law Caroline, Kergoat Marie-Jeanne, Leclerc Bernard-Simon, Panisset Michel, Postuma Ronald, Kergoat Hélène

机构信息

School of Optometry and Vision Science University of Waterloo Waterloo ON Canada.

School of Optometry University of Montréal Montréal QC Canada.

出版信息

Mov Disord Clin Pract. 2016 Nov 20;4(3):424-429. doi: 10.1002/mdc3.12453. eCollection 2017 May-Jun.

Abstract

BACKGROUND

We recently reported that convergence insufficiency (CI)-type visual symptomatology was more prevalent in participants with Parkinson's disease (PD), compared to controls. The objective of this work was to determine the prevalence of a confirmed clinical diagnosis of CI in PD, compared to controls.

METHODS

Participants with (n = 80) and without (n = 80) PD were recruited and received an eye exam. Published criteria were used to arrive at a clinical diagnosis of CI. The Convergence Insufficiency Symptom Survey (CISS-15) questionnaire was administered to each participant, with a score of ≥21 being considered positive for CI symptomatology. Student test, chi-square, or nonparametric tests at the 0.05 level were used for statistical significance.

RESULTS

A total of 43.8% of participants with versus 16.3% without PD had a clinical diagnosis of CI ( 0.001). A total of 53.8% of participants with versus 18.8% without PD had scores on the CISS-15 of ≥21 ( 0.001).

CONCLUSIONS

These results indicate that individuals with PD have a higher prevalence of CI and CI symptomatology than controls. These data provide evidence supporting the notion that treatment for symptomatic CI should be investigated in individuals with PD.

摘要

背景

我们最近报告称,与对照组相比,帕金森病(PD)患者中集合不足(CI)型视觉症状更为普遍。这项研究的目的是确定与对照组相比,PD患者中经确诊的CI临床诊断患病率。

方法

招募了患有PD(n = 80)和未患PD(n = 80)的参与者,并对他们进行了眼科检查。采用已发表的标准来做出CI的临床诊断。对每位参与者进行集合不足症状调查(CISS - 15)问卷测试,得分≥21被视为CI症状呈阳性。采用0.05水平的学生t检验、卡方检验或非参数检验来确定统计学意义。

结果

患有PD的参与者中共有43.8%被临床诊断为CI,而未患PD的参与者中这一比例为16.3%(P < 0.001)。患有PD的参与者中共有53.8%在CISS - 15上的得分≥21,而未患PD的参与者中这一比例为18.8%(P < 0.001)。

结论

这些结果表明,与对照组相比,PD患者中CI及CI症状的患病率更高。这些数据为支持在PD患者中研究症状性CI治疗的观点提供了证据。

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Parkinsonism Relat Disord. 2012 Jan;18(1):54-8. doi: 10.1016/j.parkreldis.2011.08.013. Epub 2011 Sep 14.
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