帕金森病中快速的双眼会聚眼球运动受到干扰：一项视频眼动图研究。
Fast vergence eye movements are disrupted in Parkinson's disease: A video-oculography study.
作者信息
Hanuška Jaromír, Bonnet Cecilia, Rusz Jan, Sieger Tomáš, Jech Robert, Rivaud-Péchoux Sophie, Vidailhet Marie, Gaymard Bertrand, Růžička Evžen
机构信息
Dept. of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic; Dept. of Neurosurgery, Hospital Na Homolce, Prague, Czech Republic.
Dept. of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic; AP HP, Neurology Department, Pitié Salpêtrière Hospital, Paris, France.
出版信息
Parkinsonism Relat Disord. 2015 Jul;21(7):797-9. doi: 10.1016/j.parkreldis.2015.04.014. Epub 2015 Apr 23.
BACKGROUND
Blurred near vision is a common non-motor symptom in patients with Parkinson's disease (PD), however detailed characterization of vergence eye movements (VEM) is lacking.
METHODS
Convergence and divergence were examined in 18 patients with PD and 18 control subjects using infrared video-oculography. VEM metrics analyzed included latency, velocity and accuracy, in vertical and horizontal planes.
RESULTS
The latency of convergence and divergence was significantly increased in PD subjects. Additionally, divergence was slow and hypometric, while other convergence metrics were similar to controls.
CONCLUSION
We provide evidence in favor of disrupted VEM in PD.
背景
近视模糊是帕金森病（PD）患者常见的非运动症状，然而，目前缺乏对双眼视轴汇聚眼动（VEM）的详细特征描述。
方法
使用红外视频眼动图技术对18例PD患者和18名对照者进行了集合和发散检查。分析的VEM指标包括垂直和水平平面上的潜伏期、速度和准确性。
结果
PD患者的集合和发散潜伏期显著延长。此外，发散缓慢且测距不足，而其他集合指标与对照组相似。
结论
我们提供的证据支持PD患者存在VEM障碍。
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