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孕期诊断出的性传播急性丙型肝炎感染:产后成功治疗的病例报告

Sexually acquired acute hepatitis C infection diagnosed during pregnancy: a case report of successful postpartum treatment.

作者信息

Nandi Preetha, Kalapila Aley G, Badell Martina L, Sheth Anandi N

机构信息

Emory University School of Medicine, Atlanta, GA, United States.

Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, United States.

出版信息

Case Rep Womens Health. 2018 Sep 19;20:e00080. doi: 10.1016/j.crwh.2018.e00080. eCollection 2018 Oct.

Abstract

BACKGROUND

Infection with the hepatitis C virus (HCV) during pregnancy has emerged as an increasingly recognized and prevalent condition among women of reproductive age in the United States. While screening recommendations exist for pregnant women at high risk of HCV infection, pregnant women with HCV are often under-screened, not diagnosed, or do not receive adequate follow-up, thereby increasing the risk of suboptimal maternal and infant outcomes (including in future pregnancies).

CASE

A pregnant woman living with HIV presented with intrahepatic cholestasis of pregnancy. She had tested negative for HCV earlier in pregnancy as part of routine screening recommended for women living with HIV. She was found to have sexually acquired a new HCV infection from her partner during pregnancy. She successfully completed treatment postpartum.

CONCLUSION

With the rise in HCV infection among pregnant patients, physicians should be diligent in assessing pregnant women and their partners for HCV risk factors, testing for HCV when risk is identified, and arranging follow-up testing and treatment for HCV-positive mothers and their infants.

摘要

背景

在美国,孕期丙型肝炎病毒(HCV)感染已成为育龄女性中越来越受到认可且普遍存在的情况。虽然针对HCV感染高危孕妇有筛查建议,但感染HCV的孕妇常常筛查不足、未被诊断或未得到充分随访,从而增加了母婴不良结局(包括未来妊娠时)的风险。

病例

一名感染HIV的孕妇出现了妊娠期肝内胆汁淤积症。作为对感染HIV女性的常规筛查的一部分,她在孕期早期HCV检测呈阴性。她被发现孕期通过性行为从伴侣那里感染了新的HCV。她产后成功完成了治疗。

结论

随着孕妇中HCV感染率的上升,医生应勤勉地评估孕妇及其伴侣的HCV危险因素,在确定有风险时检测HCV,并为HCV阳性母亲及其婴儿安排后续检测和治疗。

相似文献

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Hepatitis C in pregnancy: screening, treatment, and management.妊娠期丙型肝炎:筛查、治疗与管理
Am J Obstet Gynecol. 2017 Nov;217(5):B2-B12. doi: 10.1016/j.ajog.2017.07.039. Epub 2017 Aug 4.

本文引用的文献

1
Hepatitis C in pregnancy: screening, treatment, and management.妊娠期丙型肝炎:筛查、治疗与管理
Am J Obstet Gynecol. 2017 Nov;217(5):B2-B12. doi: 10.1016/j.ajog.2017.07.039. Epub 2017 Aug 4.

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