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传染性脊髓病。

Infectious Myelopathies.

机构信息

Department of Neurology, Brown University, Rhode Island Hospital, 222 Richmond Street, Providence, RI 02903, USA.

Department of Neurology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USA.

出版信息

Neurol Clin. 2018 Nov;36(4):789-808. doi: 10.1016/j.ncl.2018.06.001.

Abstract

Infectious diseases are an important cause of spinal cord dysfunction. Infectious myelopathies are of growing concern given increasing global travel and migration and expanding prevention and treatment with vaccinations, antibiotics, and antiretrovirals. Clinicians must recognize these pathologies because outcomes can dramatically improve with prompt diagnosis and management. We provide a complete review of the most frequent infectious agents that can affect the spinal cord. For each pathogen we describe epidemiology, pathophysiology, anatomic location, characteristic clinical syndromes, diagnostic approach, treatment, and prognosis. The review includes spinal imaging from selected cases.

摘要

传染病是脊髓功能障碍的一个重要原因。鉴于全球旅行和移民的增加,以及疫苗接种、抗生素和抗逆转录病毒药物的广泛应用,感染性脊髓病日益受到关注。临床医生必须认识到这些病变,因为及时诊断和治疗可以显著改善预后。我们全面回顾了最常见的可影响脊髓的感染性病原体。对于每一种病原体,我们描述了其流行病学、病理生理学、解剖部位、特征性临床综合征、诊断方法、治疗和预后。本综述包括了一些选定病例的脊髓影像学表现。

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