Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.
Semin Neurol. 2021 Jun;41(3):280-290. doi: 10.1055/s-0041-1725126. Epub 2021 May 19.
In the setting of both globalization and increasing use of immunosuppressive therapy, infectious myelopathies are an important cause of morbidity worldwide. Clinical spinal cord syndromes related to infection are varied, including transverse myelitis, acute flaccid paralysis related to anterior horn cell involvement, spinal cord compression, chronic spastic paraparesis, and myeloradiculitis. Causative pathogens include viruses, parasites, pyogenic and atypical bacteria, and fungi. The epidemiology, clinical characteristics, diagnosis, and treatment of selected organisms will be discussed in this article.
在全球化和免疫抑制治疗日益普及的背景下,感染性脊髓病是全球发病率的一个重要原因。与感染相关的临床脊髓综合征多种多样,包括横贯性脊髓炎、累及前角细胞的急性弛缓性瘫痪、脊髓压迫、慢性痉挛性截瘫和脊神经根脊髓炎。病原体包括病毒、寄生虫、化脓性和非典型细菌以及真菌。本文将讨论选定病原体的流行病学、临床特征、诊断和治疗。