Wills Siobhán S, Raston Colin L, Stubbs Keith A
School of Molecular Sciences, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
Institute for Nanoscale Science and Technology, College of Science and Engineering, Flinders University, Sturt Road, Bedford Park, SA 5042, Australia.
Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3748-3751. doi: 10.1016/j.bmcl.2018.10.015. Epub 2018 Oct 11.
A simple synthesis, which utilizes a thin film microfluidic reactor for a problematic step, of a potent inhibitor of α-N-acetylhexosaminidases, DGJNAc, has been developed.
已开发出一种简单的合成方法,该方法利用薄膜微流体反应器来进行一个关键步骤,以合成强效的α-N-乙酰己糖胺酶抑制剂DGJNAc。