Duczynski Jeremy, Raston Colin L, Stubbs Keith A
School of Molecular Sciences, University of Western Australia Crawley WA 6009 Australia
Flinders Institute for Nanoscale Science and Technology, College of Science and Engineering, Flinders University Bedford Park SA 5042 Australia.
RSC Adv. 2022 Aug 17;12(36):23162-23168. doi: 10.1039/d2ra04409a. eCollection 2022 Aug 16.
Iminosugars are important compounds in the area of carbohydrate-based therapeutics. A simple synthetic methodology utilizing the vortex fluidic thin film microfluidic reactor is effective in the synthesis of such compounds for diverse reaction types, with the optimal tilt angle of the reactor at 45° and the optimal rotational speed dependent on the nature of the liquid.
亚氨基糖是基于碳水化合物的治疗领域中的重要化合物。一种利用涡旋流体薄膜微流控反应器的简单合成方法,对于多种反应类型的此类化合物的合成是有效的,反应器的最佳倾斜角度为45°,最佳转速取决于液体的性质。