Wick Mark R
Divisions of Surgical Pathology & Cytopathology and Autopsy Pathology, University of Virginia Medical Center, 1215 Lee St., Charlottesville, VA 22908-0214, USA.
Semin Diagn Pathol. 2018 Nov;35(6):354-359. doi: 10.1053/j.semdp.2018.10.007. Epub 2018 Oct 16.
Histochemistry has a history which, in some ways, goes back to ancient times. The desire for humans to understand the workings of their bodies, and the roles that various chemicals have in them, is long-standing. This review considers the evolution of histochemistry and cytochemistry as scientific disciplines, culminating in the pairing of those techniques with basic biochemistry. They have served as the bases for a synthesis of microscopy, chemistry, immunology, and molecular biology, particularly in the practice of anatomic pathology.
组织化学有着一段在某些方面可追溯到古代的历史。人类想要了解自身身体的运作方式以及各种化学物质在其中所起作用的愿望由来已久。本综述探讨了组织化学和细胞化学作为科学学科的发展历程，最终这些技术与基础生物化学相结合。它们已成为显微镜学、化学、免疫学和分子生物学综合的基础，尤其是在解剖病理学实践中。
