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编码五种结核分枝杆菌蛋白质的基因的分离及限制性酶切图谱

Isolation and restriction site maps of the genes encoding five Mycobacterium tuberculosis proteins.

作者信息

Shinnick T M, Krat C, Schadow S

出版信息

Infect Immun. 1987 Jul;55(7):1718-21. doi: 10.1128/iai.55.7.1718-1721.1987.

DOI:10.1128/iai.55.7.1718-1721.1987
PMID:3036711
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC260584/
Abstract

A series of recombinant phage expressing five Mycobacterium tuberculosis antigens were isolated. Restriction maps for these antigens were deduced, and the size of the expressed proteins was determined.

摘要

分离出一系列表达五种结核分枝杆菌抗原的重组噬菌体。推导了这些抗原的限制性图谱，并确定了表达蛋白的大小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a21/260584/b4843a468a9f/iai00091-0190-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a21/260584/b4843a468a9f/iai00091-0190-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a21/260584/b4843a468a9f/iai00091-0190-a.jpg

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本文引用的文献

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The immunology of mycobacterial infections.分枝杆菌感染的免疫学
Crit Rev Microbiol. 1982;9(2):139-97. doi: 10.3109/10408418209104488.
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Production and characterization of monoclonal antibodies to Mycobacterium tuberculosis, M. bovis (BCG) and M. leprae.结核分枝杆菌、牛分枝杆菌（卡介苗）和麻风分枝杆菌单克隆抗体的制备与鉴定
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The humoral immune response in tuberculosis: its nature, biological role and diagnostic usefulness.结核病中的体液免疫反应：其本质、生物学作用及诊断价值。
结核分枝杆菌表达两种伴侣蛋白60同源物。
Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2608-12. doi: 10.1073/pnas.90.7.2608.
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The Mycobacterium tuberculosis 65-kilodalton antigen is a heat shock protein which corresponds to common antigen and to the Escherichia coli GroEL protein.结核分枝杆菌65千道尔顿抗原是一种热休克蛋白，它与共同抗原及大肠杆菌GroEL蛋白相对应。
Infect Immun. 1988 Feb;56(2):446-51. doi: 10.1128/iai.56.2.446-451.1988.
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The Mycobacterium tuberculosis BCG-a protein has homology with the Escherichia coli GroES protein.结核分枝杆菌卡介苗-a蛋白与大肠杆菌GroES蛋白具有同源性。
Nucleic Acids Res. 1989 Feb 11;17(3):1254. doi: 10.1093/nar/17.3.1254.
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Isolation and characterization of recombinant lambda gt11 bacteriophages expressing eight different mycobacterial antigens of potential immunological relevance.表达八种具有潜在免疫相关性的不同分枝杆菌抗原的重组λgt11噬菌体的分离与鉴定。
Infect Immun. 1988 May;56(5):1344-51. doi: 10.1128/iai.56.5.1344-1351.1988.
7
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Infect Immun. 1991 Feb;59(2):665-70. doi: 10.1128/iai.59.2.665-670.1991.
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10
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DNA. 1985 Feb;4(1):39-49. doi: 10.1089/dna.1985.4.39.