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["终末期”脱水,第2部分:医学指征与治疗方法]

["Terminal" dehydration, part 2 : Medical indications and therapeutic approach].

作者信息

Suchner U, Reudelsterz C, Gog C

机构信息

Klinik für Anästhesiologie und operative Intensivmedizin, Klinikum Darmstadt, Darmstadt, Deutschland.

, Berlin, Deutschland.

出版信息

Anaesthesist. 2018 Nov;67(11):879-892. doi: 10.1007/s00101-018-0502-x.

DOI:10.1007/s00101-018-0502-x
PMID:30367210
Abstract

The approach in the clinical fluid management of the dying is still controversially discussed in specialist circles and also in the general population. In this article the importance of establishing the therapeutic indications is emphasized against the background of a lack of evidence. Options to achieve noninvasive objectification of assumed dehydration as well as assessment of the reversibility of the symptoms are shown and the importance of monitoring of all therapeutic actions is discussed. The pathophysiological foundation of reversible disorders of fluid homoeostasis are described and distinguished from the irreversible disorders leading to terminal dehydration. If clinically assisted hydration (CAH) is indicated, the hydration status must be assessed individually as well as in advance and all therapeutic measures must be constantly adjusted to the results of non-invasive monitoring procedures.

摘要

临终患者临床液体管理的方法在专业领域乃至普通大众中仍存在争议。本文在缺乏证据的背景下,强调了确立治疗指征的重要性。展示了实现对假定脱水进行非侵入性客观评估的方法以及对症状可逆性的评估,并讨论了监测所有治疗措施的重要性。描述了液体稳态可逆性紊乱的病理生理基础,并将其与导致终末期脱水的不可逆紊乱区分开来。如果需要进行临床辅助水化(CAH),则必须对水化状态进行个体评估和预先评估,并且所有治疗措施都必须根据非侵入性监测程序的结果不断调整。

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1
["Terminal" dehydration, part 2 : Medical indications and therapeutic approach].["终末期”脱水,第2部分:医学指征与治疗方法]
Anaesthesist. 2018 Nov;67(11):879-892. doi: 10.1007/s00101-018-0502-x.
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How to manage terminal dehydration.如何处理终末期脱水。
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The Association of Hyponatremia, Risk of Confusional State, and Mortality.低钠血症、意识模糊状态风险与死亡率的关联
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Indications and practice of artificial hydration for terminally ill cancer patients.晚期癌症患者人工补液的适应证与实践
Curr Opin Support Palliat Care. 2014 Dec;8(4):358-63. doi: 10.1097/SPC.0000000000000089.
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The volume of hydration in terminally ill cancer patients with hydration-related symptoms: a prospective study.患有与水化相关症状的晚期癌症患者的水化量:一项前瞻性研究。
J Palliat Med. 2014 Sep;17(9):1037-41. doi: 10.1089/jpm.2013.0557. Epub 2014 Jul 22.
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Circulatory shock.循环性休克
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