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["终末期"脱水:鉴别诊断与证据主体]

["Terminal" dehydration : Differential diagnosis and body of evidence].

作者信息

Suchner U, Reudelsterz C, Gog C

机构信息

Klinik für Anästhesiologie und operative Intensivmedizin, Klinikum Darmstadt, Darmstadt, Deutschland.

, Berlin, Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2019 May;114(4):355-368. doi: 10.1007/s00063-019-0583-6.

Abstract

Dehydration in palliative care patients can be associated with increased morbidity and mortality and is nevertheless therapeutically controversial. This article provides an overview of possible causes of dehydration at the end of life and places special emphasis on "terminal" dehydration in the dying. Empirical attitudes of healthcare professionals and persons concerned (patients and relatives) as well as evidence-based findings on "terminal" dehydration are elucidated and the limitations are described. Finally, it is concluded that the appropriate detection of the mode of dehydration (including its underlying pathophysiology) as well as the clinical evaluation of the "reversibility" of the symptoms after fluid therapy, is of central importance in establishing the indications for clinically assisted hydration (CAH).

摘要

姑息治疗患者的脱水可能与发病率和死亡率增加相关,然而在治疗上存在争议。本文概述了临终时脱水的可能原因,并特别强调濒死期的“终末期”脱水。阐述了医护人员及相关人员(患者和亲属)的经验性态度以及关于“终末期”脱水的循证研究结果,并描述了其局限性。最后得出结论,在确定临床辅助补液(CAH)的指征时,正确检测脱水模式(包括其潜在病理生理学)以及对补液治疗后症状“可逆性”的临床评估至关重要。

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