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通过介电泳扩展不同尺寸颗粒间相互作用的动力学模拟的灵活性。

Expanding the flexibility of dynamics simulation on different size particle-particle interactions by dielectrophoresis.

作者信息

Hu Sheng, Fu Rongrong

机构信息

College of Information Science and Engineering, Northeastern University, Shenyang, China.

Measurement Technology and Instrumentation Key Lab of Hebei Province, Yanshan University, Qinhuangdao, 066004, China.

出版信息

J Biol Phys. 2019 Mar;45(1):45-62. doi: 10.1007/s10867-018-9514-7. Epub 2018 Oct 26.

DOI:10.1007/s10867-018-9514-7
PMID:30367339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6408558/
Abstract

In this paper, we perform flexible and reliable dynamics simulations on different sizes of two or more particles' interactive motions, where they encounter positive or negative dielectrophoresis (DEP) forces. The particles with identical or non-identical size are in close proximity suspended freely in a solution under a homogeneous electric field. According to the description of classic dipole moment, DEP forces make the particles form a straight chain. Therefore, dynamics simulation based on Newton's laws is utilized to understand AC DEP phenomena among multiple particles. To solve the relevant governing equations, Stokes drag and repulsive forces (including wall and particles) are combined with DEP forces to obtain the trajectories of particles. Results show that particles with the same sign of the Clausius-Mossotti (CM) factor revolve clockwise or counterclockwise to attract each other parallel to the electric field direction. Conversely, the particle chain is perpendicular to the field. This programmable advantage is of great benefit to the study of three or four particle motions. Meanwhile, the pearl chain consisting of three or four particles is related not only to an individual CM factor but also to initial spatial configuration. Both the cluster and short chain are dependent on symmetry between the geometric distribution and electric field, while it implies different size particles easily cause the chain structure with less time.

摘要

在本文中,我们对不同尺寸的两个或多个粒子的相互作用运动进行了灵活且可靠的动力学模拟,这些粒子会受到正或负的介电泳(DEP)力。尺寸相同或不同的粒子在均匀电场下自由悬浮于溶液中且彼此靠近。根据经典偶极矩的描述,DEP力使粒子形成一条直线链。因此,利用基于牛顿定律的动力学模拟来理解多个粒子间的交流介电泳现象。为求解相关控制方程,将斯托克斯阻力和排斥力(包括壁面和粒子间的)与DEP力相结合以获得粒子的轨迹。结果表明,具有相同克劳修斯 - 莫索蒂(CM)因子符号的粒子会顺时针或逆时针旋转,以在平行于电场方向上相互吸引。相反,粒子链垂直于电场。这种可编程的优势对研究三个或四个粒子的运动非常有益。同时,由三个或四个粒子组成的珍珠链不仅与单个CM因子有关,还与初始空间构型有关。簇和短链都依赖于几何分布与电场之间的对称性,而这意味着不同尺寸的粒子更容易在更短时间内形成链结构。

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本文引用的文献

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Estimation of the physical properties of neurons and glial cells using dielectrophoresis crossover frequency.利用介电泳交叉频率估算神经元和神经胶质细胞的物理特性。
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